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merck millipore,默克密理博,MABN686,Anti-CCT2 Antibody, clone 5B5C4
产品名称：Anti-CCT2 Antibody, clone 5B5C4
产品型号：MABN686
Anti-CCT2 Antibody, clone 5B5C4 is a highly specific mouse monoclonal antibody, that targets T-complex protein 1 subunit beta & has been tested in western blotting, Immunofluorescence & Flow Cytometry More>>
merck millipore,默克密理博,MABN686,Anti-CCT2 Antibody, clone 5B5C4
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Mk, H, M, R FC, WB M Ascites Monoclonal Antibody 描述 产品目录编号 MABN686 描述 Anti-CCT2 Antibody, clone 5B5C4 Alternate Names - CCT2
- T-complex protein 1 subunit beta
背景信息 T-complex protein 1 subunit beta (TCP-1-beta) or alternatively known as CCT-beta which is encoded by the human gene named CCT2 or 99D8.1, is a protein that plays a role as a molecular chaperone. This means that CCT2 assists in the non-covalent folding or unfolding and the assembly or disassembly of other macromolecular structures, but does not occur in these structures when the structures are performing their normal biological functions. In the case of CCT2 it assists in the folding of various proteins including actin and tubulin, two very important cytoskeletal proteins in all cells. CCT2 is cytoplasmically expressed in mammalian cells, and CCT2 in worms at least, CCT2 is expressed in most, if not all, tissues. Moreover via inhibition assays in worms, CCT2 is required for a variety of functions including normal transgene repression and subcellular localization events, embryonic osmotic integrity, embryonic and larval viability, fertility, vulval development, and body color. In humans, CCT2 is also a component of a huge multi-protein complex called the BBS/CCT (BBSome) complex which is composed of several proteins named MKKS, BBS10, BBS12, TCP1, CCT3, CCT4, CCT5, and CCT8, that forms part of the cilia. It is thought that CCT2 may play a role in the assembly of the BBSome which is needed for ciliogenesis, and CCT2 appears to regulate the transport of vesicles to the cilia. EMD-Millipore’s Anti-CCT2 mouse monoclonal antibody has been tested in western blot against recombinant protein as well as cell lysates from HeLa, MCF-7, Jurkat, T47, K562, A431, NIH3T3, PC-12 and COS7 cells. The antibody has also been successfully tested in fluorescent immunocytochemistry on 3T3-L1 cells and in flow cytometry on NIH3T3 cells in culture and in direct ELISA on varying concentrations of recombinant antigen. 产品信息 格式 Ascites 控制 - HeLa, MCF-7, Jurkat, T47D, K562, A431, NIH/3T3, PC-12 and Cos7 cell lysates
演示 Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide. 应用 应用 Anti-CCT2 Antibody, clone 5B5C4 is a highly specific mouse monoclonal antibody, that targets T-complex protein 1 subunit beta & has been tested in western blotting, Immunofluorescence & Flow Cytometry. 主要应用 - Flow Cytometry
- Western Blotting
应用说明 Flow cytometry analysis: A 1:200-400 dilution from a representative lot detected CCT2 in NIH/3T3 cells.
Immunofluorescence Analysis: A 1:200-1,000 dilution from a representative lot detected CCT2 in 3T3-L1 cells.
Optimal working dilutions must be determined by end user.
生物信息 免疫原品种 Purified recombinant fragment of human CCT2 expressed in E. Coli. 克隆 5B5C4 宿主 Mouse 同种型 IgG1 品种反应性 MonkeyHumanMouseRat 抗体类型 Monoclonal Antibody 基因符号 - TCP-1-beta
- CCTB
- 99D8.1
- PRO1633
- CCT-beta
- MGC142074
- MGC142076
纯化方法 Unpurified UniProt编号 - P78371
产品使用声明 质量保证 Evaluated by Western Blotting in HeLa, MCF-7, Jurkat, T47D, K562, A431, NIH/3T3, PC-12, and Cos7 cell lysates.
Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected CCT2 in Hela, MCF-7, Jurkat, T47D, K562, A431, NIH/3T3, PC-12, and Cos7 cell lysates.
使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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