merck millipore,默克密理愽
  • merck millipore,默克密理博,MABN236,Anti-Inducible NO synthase Antibody, clone 4E6.1

  • merck millipore,默克密理博,MABN236,Anti-Inducible NO synthase Antibody, clone 4E6.1

    产品名称：Anti-Inducible NO synthase Antibody, clone 4E6.1
    产品型号：MABN236
    Detect iNOS/NOS II using this mouse monoclonal antibody, Anti-Inducible NO synthase Antibody & clone 4E6.1 validated for use in western blotting.

    merck millipore,默克密理博,MABN236,Anti-Inducible NO synthase Antibody, clone 4E6.1

  • 产品介绍
  • merck millipore,默克密理博,MABN236,Anti-Inducible NO synthase Antibody, clone 4E6.1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    MWBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABN236
    描述 Anti-Inducible NO synthase Antibody, clone 4E6.1
    Alternate Names
    • MAC-NOS
    • Inducible NOS,iNOS,Macrophage NOS
    • NOS type II
    • Peptidyl-cysteine S-nitrosylase NOS2
    • Nitric oxide synthase, inducible
    • Inducible NO synthase
    背景信息 Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO. NO production is mediated by members of the nitric oxide synthase (NOS) family. NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) & endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned. Cytokines such as interferon-gamma (IFN), tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels. Protein kinase C-stimulating agents exhibit the same effect on iNOS activity. Human iNOS is regulated by calcium/calmodulin (in contrast with mouse NOS2).
    产品信息
    格式 Purified
    演示 Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Detect iNOS/NOS II using this mouse monoclonal antibody, Anti-Inducible NO synthase Antibody & clone 4E6.1 validated for use in western blotting.
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to the N-terminus of mouse Inducible NO synthase.
    克隆 4E6.1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG2a
    品种反应性 Mouse
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_035057
    基因符号
    • Inosl
    • Nos2
    纯化方法 Protein G purified
    UniProt编号
    • P29477
    产品使用声明
    质量保证 Evaluated by Western Blotting in RAW264.7 cell lysate.

    Western Blotting Analysis: 0.2 µg/mL of this antibody detected Inducible NO synthase in 10 µg of IFN gamma/LPS treated RAW264.7 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABN236,Anti-Inducible NO synthase Antibody, clone 4E6.1

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