• merck millipore,默克密理博,516620,Peroxynitrite - Calbiochem
  • merck millipore,默克密理博,516620,Peroxynitrite - Calbiochem

    产品名称:Peroxynitrite - Calbiochem
    产品型号:516620
    Synthesized from isoamyl nitrite and hydrogen peroxide.

    merck millipore,默克密理博,516620,Peroxynitrite - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,516620,Peroxynitrite - Calbiochem

    重要规格表

    描述
    概述 Synthesized from isoamyl nitrite and hydrogen peroxide. Peroxynitrite (ONOO) is a cell-permeable strong biological oxidizing agent that reacts with DNA, membrane phospholipids, sulfhydryl groups, and tyrosine. Has been implicated in a variety of pathophysiological conditions including acute respiratory distress syndrome (ARDS), arthritis, atherosclerosis, inflammatory bowel disease, ischemia-reperfusion, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated neurotoxicity, and septic shock.
    Note: 1 set = 2 x 1 ml.
    产品目录编号 516620
    品牌系列 Calbiochem®
    参考
    参考 Marla, S.S., et al. 1997. Proc. Natl. Acad. Sci. USA 94, 14243.
    Sakuma, S., et al. 1997. Biochem. Biophys. Res. Commun. 230, 476.
    Lymar, S.V., et al. 1996. Biochemistry 35, 7855.
    Uppu, R.M., and Pryor, W.A. 1996. Methods Enzymol. 269, 322.
    Ischiropoulos, H., and al-Medhi, A.B. 1995. FEBS Lett. 364, 279.
    产品信息
    具有ATP竞争性 N
    形式 Yellow liquid
    配方 Supplied in 4.7% NaOH at 160-200 mM.
    Molar Mass 85.0
    可逆 N
    生物信息
    主靶 Oxidizing agent that reacts with DNA, membrane phospholipids, sulfhydryl groups, and tyrosine
    理化信息
    细胞可渗透 Y
    安全信息
    R相 R: 8-20/22-34

    Contact with combustible material may cause fire.
    Harmful by inhalation and if swallowed.
    Causes burns.
    S相 S: 3-28-36/37/39-45

    Keep in a cool place.

    Wear suitable protective clothing, gloves and eye/face protection.
    In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Oxidizer
    有害材料注意事项: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
    储存 ≤ -70°C
    避光 Protect from light
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Protect from heat, light, metal ions, and air. Peroxynitrite is unstable; thaw rapidly, dispense into aliquots, purge tubes with an inert gas, and freeze -70°C. Activity decreases ~2% /day at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,516620,Peroxynitrite - Calbiochem

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