• merck millipore,默克密理博,MABN606,Anti-Laforin Antibody, clone N84/37
  • merck millipore,默克密理博,MABN606,Anti-Laforin Antibody, clone N84/37

    产品名称:Anti-Laforin Antibody, clone N84/37
    产品型号:MABN606
    Detect Laforin using this mouse monoclonal antibody, Anti-Laforin Antibody, clone N84/37 validated for use in western blotting & IHC.

    merck millipore,默克密理博,MABN606,Anti-Laforin Antibody, clone N84/37

  • 产品介绍
  • merck millipore,默克密理博,MABN606,Anti-Laforin Antibody, clone N84/37

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABN606
    Replaces MABN1050
    描述 Anti-Laforin Antibody, clone N84/37
    Alternate Names
    • LAFPTPase
    • Laforin
    • Lafora PTPase
    背景信息 Laforin, also known as Lafora PTPase, is a dual specificity protein phosphatase. Laforin is involved in the control of glycogen metabolism, specifically in preventing the formation of poorly branched glycogen molecules (polyglucosans). Laforin forms a complex with NHLRC1/malin and HSP70 that suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system (UPS). Laforin is expressed in heart, skeletal muscle, kidney, pancreas and brain. Defective Laforin is linked to progressive myoclonic epilepsy type 2 (EPM2).
    产品信息
    格式 Purified
    控制
    • Human skeletal muscle tissue lysate
    演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Detect Laforin using this mouse monoclonal antibody, Anti-Laforin Antibody, clone N84/37 validated for use in western blotting & IHC.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:50-250 dilution from a representative lot detected Laforin in human brain and human kidney tissue.
    生物信息
    免疫原品种 Recombinant protein corresponding to human Laforin.
    克隆 N84/37
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG1κ
    品种反应性 Human
    Species Reactivity Note Demonstrated to react with Human. Other homologies: Mouse (89% sequence homology)
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_001018051
    基因符号
    • EPM2A
    纯化方法 Protein G purified
    UniProt编号
    • O95278
    产品使用声明
    质量保证 Evaluated by Western Blotting in human skeletal muscle tissue lysate.

    Western Blotting Analysis: 0.5 µg/mL of this antibody detected Laforin in 200 µg of human skeletal muscle tissue lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABN606,Anti-Laforin Antibody, clone N84/37

上一件merck millipore产品:merck millipore,默克密理博,14-759,Abl (Y253F) Protein, active, 10 µg
下一件merck millipore产品:merck millipore,默克密理博,AB5491-200UL,Anti-Calcium Channel Cav3.1 Antibody



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