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merck millipore,默克密理博,MABN516,Anti-TARPGamma2/4/8 Antibody, clone N245/36
产品名称:Anti-TARPGamma2/4/8 Antibody, clone N245/36
产品型号:MABN516
Detect TARP Gamma using this mouse monoclonal antibody, Anti-TARPGamma2/4/8 Antibody & clone N245/36 validated for use in western blotting.
merck millipore,默克密理博,MABN516,Anti-TARPGamma2/4/8 Antibody, clone N245/36
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M WB M Purified Monoclonal Antibody 描述 产品目录编号 MABN516 描述 Anti-TARPGamma2/4/8 Antibody, clone N245/36 Alternate Names - TARP gamma-2
- Voltage-dependent calcium channel gamma-2 subunit
- Neuronal voltage-gated calcium channel gamma-2 subunit
- Transmembrane AMPAR regulatory protein gamma-2
背景信息 Transmembrane AMPAR regulatory protein gamma-2/4/8 (TARPGamma 2/4/8) is also called Voltage-dependent calcium channel gamma-2/4/8 subunit and Neuronal voltage-gated calcium channel gamma-2/4/8 subunit (CACNG2/4/8). TARPGamma 2/4/8 regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). TARPGamma 2/4/8 promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. TARPGamma 2/4/8 is thought to stabilize the calcium channel in an inactivated or closed state. 产品信息 格式 Purified 控制 - Mouse brain tissue lysate
演示 Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect TARP Gamma using this mouse monoclonal antibody, Anti-TARPGamma2/4/8 Antibody & clone N245/36 validated for use in western blotting. 主要应用 - Western Blotting
应用说明 Western Blotting Analysis: A representative lot detected TARPGamma2/4/8, but did not cross react with TARPGamma3 in COS cells transiently transfected with GFPtagged-TARPGamma2/3/4/8 (Prof. J. Trimmer, University of California, Davis.). 生物信息 免疫原品种 Recombinant protein corresponding to the C-terminus of rat TARPGamma2/4/8. 表位 C-terminus 克隆 N245/36 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 This antibody recognizes the C-terminus of TARPGamma2. This antibody cross reacts with TARPGamma4 and TARPGamma8, but it does not cross react with TARPGamma3 (Prof. J. Trimmer, University of California, Davis.). 同种型 IgG2aκ 品种反应性 Mouse Species Reactivity Note Demonstrated to react with Mouse. Predicted to react with Rat based on immunogen design. Other homologies: Human (96% sequence homology). 抗体类型 Monoclonal Antibody 基因符号 - Gacng2
纯化方法 Protein G purified UniProt编号 - Q71RJ2
产品使用声明 质量保证 Evaluated by Western Blotting in mouse brain tissue lysate.
Western Blotting analysis: 1 µg/mL of this antibody detected TARPGamma2/4/8 in 10 µg of mouse brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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