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品种反应性 主要应用 宿主 格式 抗体类型 H WB M Purified Monoclonal Antibody 描述 产品目录编号 MABN356 描述 Anti-FKBP4 Antibody, clone 2H9.1 Alternate Names - Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed
- FK506
- FK506-binding protein
- Peptidyl-prolyl cis-trans isomerase FKBP4
- PPIase FKBP4
- 51 kDa FK506-binding protein
- FKBP51
- 52 kDa FK506-binding protein
- 52 kDa FKBP
- FKBP-52
- 59 kDa immunophilin
- p59
- FK506-binding protein 4
- FKBP-4
- FKBP59
- HSP-binding immunophilin
- HBI
- Immunophilin FKBP52
- Rotamase
背景信息 FKBP4, also known as Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4), or 51 kDa FK506-binding protein (FKBP51), 52 kDa FK506-binding protein (FKBP-52), or 59 kDa immunophilin (p59), or FK506-binding protein 4 (FKBP-4) or FKBP59 , or HSP-binding immunophilin (HBI), or Immunophilin FKBP52 Rotamase, and encoded by the gene FKBP4/FKBP62 is a chaperon type protein that is involved in protein folding and trafficking and the immunoregulation of cellular responses. FKBP4 is a member of the immunophilin family of proteins. FKBP4 forms a component of unligated steroid receptors complexes and helps in the cycling of the receptors between the cytoplasm and nuclear compartments. FKBP4 also plays a role in regulating neuronal growth cones via the regulations of TRPC1 channels, and FKBP4 modules microtubule dynamics by inhibiting MAPT/TAU in microtubule assembly. Finally, FKBP4 also influences the regulation and modulation oxidative stress in mitochondria. FKBP4 will localize to the cytoplasm, mitochondria or nucleus depending upon cellular situation and is widely expressed. 产品信息 格式 Purified 演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-FKBP4 Antibody, clone 2H9.1 is an antibody against FKBP4 for use in western blotting & IHC (Paraffin). 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected FKBP4 in human testis and human cerebellum tissue. 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to the C-terminus of human FKBP4. 表位 C-terminus 克隆 2H9.1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_002005
基因符号 - FKBP52
- FKBP4
纯化方法 Protein G purified UniProt编号 - Q02790
产品使用声明 质量保证 Evaluated by Western Blotting in T47D cell lysate.
Western Blotting Analysis: 0.25 µg/mL of this antibody detected FKBP4 in 10 µg of T47D cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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下一件merck millipore产品：merck millipore,默克密理博,401474,IKK Inhibitor II, Wedelolactone - CAS 524-12-9 - Calbiochem
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