merck millipore,默克密理愽
  • merck millipore,默克密理博,MABN291,Anti-IMPDH1 Antibody, clone 4F9.1

  • merck millipore,默克密理博,MABN291,Anti-IMPDH1 Antibody, clone 4F9.1

    产品名称：Anti-IMPDH1 Antibody, clone 4F9.1
    产品型号：MABN291
    Anti-IMPDH1 Antibody, clone 4F9.1 is a highly specific mouse monoclonal antibody, that targets Inosine-5'-monophosphate dehydrogenase 1 & has been tested in western blotting & IHC.

    merck millipore,默克密理博,MABN291,Anti-IMPDH1 Antibody, clone 4F9.1

  • 产品介绍
  • merck millipore,默克密理博,MABN291,Anti-IMPDH1 Antibody, clone 4F9.1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, H, RIHC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABN291
    描述 Anti-IMPDH1 Antibody, clone 4F9.1
    Alternate Names
    • IMPDH-I
    • Inosine-5'-monophosphate dehydrogenase 1
    • IMP dehydrogenase 1
    • IMPD 1
    • IMPDH 1
    背景信息 Inosine-5'-monophosphate dehydrogenase 1 (IMPDH 1) catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), as part of the de novo synthesis of guanine nucleotides. It therefore is crucial in the regulation of cell growth. IMPDH 1 may also have single-stranded nucleic acid-binding activity involving it in RNA and/or DNA metabolism, and is suspected to play a role in the growth progression of some tumors. Defects in IMPDH 1 abnormalities are linked to retinitis pigmentosa type 10 (RP10) and Leber congenital amaurosis type 11 (LCA11). Due to the connection between IMPDH activity and cell proliferation, it has been become a target for cancer and viral chemotherapy and immunosuppressive drugs. The activities of the antitumor drug tiazofurin, the antiviral drug ribavirin, and the immunosuppressive drugs mizoribine and mycophenolic acid (MPA) are attributed to the inhibition of IMPDH. In addition, bacterial and parasitic IMPDH's differ significantly from mammalian enzymes, which make it a suitable target for anti-infective drugs.
    产品信息
    格式 Purified
    控制
    • PC-12 cell lysate
    演示 Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-IMPDH1 Antibody, clone 4F9.1 is a highly specific mouse monoclonal antibody, that targets Inosine-5'-monophosphate dehydrogenase 1 & has been tested in western blotting & IHC.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Western Blotting Analysis: 1.0 µg/mL from a representative lot detected IMPDH1 in 10 µg of NIH3T3 cell lysate.
    Western Blotting Analysis: 1.0 µg/mL from a representative lot detected IMPDH1 in 10 µg of Jurkat cell lysate.
    Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected IMPDH1 in rat eye tissue.
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to human IMPDH1.
    克隆 4F9.1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG2bκ
    品种反应性 MouseHumanRat
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_001096075
    基因符号
    • IMPD1
    • IMPDH1
    纯化方法 Protein G purified
    UniProt编号
    • P20839
    产品使用声明
    质量保证 Evaluated by Western Blotting in PC-12 cell lysate.

    Western Blotting Analysis: 1.0 µg/mL of this antibody detected IMPDH1 in 10 µg of PC-12 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABN291,Anti-IMPDH1 Antibody, clone 4F9.1

上一件merck millipore产品：merck millipore,默克密理博,ABC821,Anti-AMBRA1 Antibody
下一件merck millipore产品：merck millipore,默克密理博,MAB3060,Anti-Paxillin Antibody, clone 349


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