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merck millipore,默克密理博,MABN269,Anti-IRF8 Antibody, clone 8C6.2
产品名称：Anti-IRF8 Antibody, clone 8C6.2
产品型号：MABN269
Detect IRF-8 using this mouse monoclonal antibody, Anti-IRF8 Antibody, clone 8C6.2 validated for use in western blotting & IHC.
merck millipore,默克密理博,MABN269,Anti-IRF8 Antibody, clone 8C6.2
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABN269 描述 Anti-IRF8 Antibody, clone 8C6.2 Alternate Names - ICSBP
- Interferon regulatory factor 8
- IRF-8
- Interferon consensus sequence-binding protein
- H-ICSBP
背景信息 Interferon regulatory factor 8 (IRF-8) is also known as interferon consensus sequence-binding protein. Interferon regulatory factors (IRFs) comprise a family of transcription factors that function with the Jak/Stat pathway to regulate interferon (IFN) and IFN-inducible gene expression in response to viral infection. IRF-8 specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes at the interferon consensus sequence (ICS). IRF-8 has a negative regulatory function in immune cells, can be induced by IFNG/ IFN-gamma and is involved in CD8+ dendritic cell differentiation. IRF-8 is predominantly expressed in lymphoid tissues. IRF-8 is implicated in MS. 产品信息 格式 Purified 控制 - THP-1 cell lysate
演示 Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide. 应用 应用 Detect IRF-8 using this mouse monoclonal antibody, Anti-IRF8 Antibody, clone 8C6.2 validated for use in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western Blotting Analysis: 1.0 µg/mL from a representative lot detected IRF8 in 10 µg of human spleen tissue lysate.
Western Blotting Analysis: 1.0 µg/mL from a representative lot detected IRF8 in 10 µg of Jurkat cell lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected IRF8 in human tonsil tissue.生物信息 免疫原品种 Linear peptide corresponding to human IRF8. 克隆 8C6.2 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgMκ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_002154
基因符号 - ICSBP1
- IRF8
纯化方法 Purified by ion-exchange chromatography UniProt编号 - Q02556
产品使用声明 质量保证 Evaluated by Western Blotting in THP-1 cell lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected IRF8 in 10 µg of THP-1 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,06-709,Anti-Gq/11α Antibody, CT
下一件merck millipore产品：merck millipore,默克密理博,ELI-002-M,IL-2 ELISPOT Antibody Pair, Mouse
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