merck millipore,默克密理博,MABN1041,Anti-TAB3 Antibody, clone EPR5965, rabbit monoclonal

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merck millipore,默克密理博,MABN1041,Anti-TAB3 Antibody, clone EPR5965, rabbit monoclonal
产品名称：Anti-TAB3 Antibody, clone EPR5965, rabbit monoclonal
产品型号：MABN1041
Anti-TAB3 Antibody, clone EPR5965 is a highly specific rabbit monoclonal antibody, that targets TAB3 & has been tested in western blotting & Immunofluorescence.

merck millipore,默克密理博,MABN1041,Anti-TAB3 Antibody, clone EPR5965, rabbit monoclonal

产品介绍

merck millipore,默克密理博,MABN1041,Anti-TAB3 Antibody, clone EPR5965, rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
M, H	WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABN1041
描述	Anti-TAB3 Antibody, clone EPR5965, rabbit monoclonal
Alternate Names	TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 NF-kappa-B-activating protein 1 TAK1-binding protein 3 TAB-3 TGF-beta-activated kinase 1-binding protein 3
背景信息	TAB3 protein, or alternatively known as TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, NF-kappa-B-activating protein 1, TAK1 binding protein 3 (TAB-3), TGF-beta-activated kinase 1-binding protein 3 and encoded by the human gene named TAB3 or MAP3K7IP3 is a coordinating linker kinase in the TNF and IL-1 signaling pathways and also plays a role in the activation of the NF-kappa-B and AP1 gene activation pathways. These pathways play critical roles in many cellular pathways including immune responses, stress responses, apoptosis, proliferation and differentiation, and dysfunction of these pathways has been associated with numerous cancer and immune disorders. TAB3 is also involved in general MAPK activations and receptor signaling pathways, and TAB3 is important in Toll-like receptor signaling as well. TAB3 interacts with signaling partners TRAF6 and TRAF2 as well as TAB1, TAB2, and MAP3K7. The kinase is widely expressed in most tissues, and particularly upregulated in various cancer tissues. EMD-Millipore’s Anti-TAB3 rabbit monoclonal antibody has been tested in western blot against 293T, HepG2, HeLa, Caco-2, RAW264.7 and NIH3T3 cell lysates and in fluorescent immunocytochemistry on HepG2 cells in culture.

产品信息
格式	Unpurified
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	Anti-TAB3 Antibody, clone EPR5965 is a highly specific rabbit monoclonal antibody, that targets TAB3 & has been tested in western blotting & Immunofluorescence.
主要应用	Western Blotting
应用说明	Immunofluorescence Analysis: A 1:50 dilution from a representative lot detected TAB3 in HepG2 cells.

生物信息
免疫原品种	Synthetic peptide corresponding to human TAB3.
克隆	EPR5965
宿主	Rabbit
品种反应性	MouseHuman
抗体类型	Monoclonal Antibody
基因符号	MAP3K7IP3 TAB3
纯化方法	Unpurified
UniProt编号	Q8N5C8

产品使用声明
质量保证	Evaluated by Western Blotting in HEK293T, HepG2, HeLa, Caco-2, RAW264.7, and NIH/3T3 cell lysates. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected TAB3 in HEK293T, HepG2, HeLa, Caco-2, RAW264.7, and NIH/3T3 cell lysates. Optimal working dilutions must be determined by end user.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.