merck millipore,默克密理愽
  • merck millipore,默克密理博,MABF334,Anti-IL-2 (human) Antibody, FITC, clone MQ1-17H12

  • merck millipore,默克密理博,MABF334,Anti-IL-2 (human) Antibody, FITC, clone MQ1-17H12

    产品名称：Anti-IL-2 (human) Antibody, FITC, clone MQ1-17H12
    产品型号：MABF334
    Anti-IL-2 (human) Antibody, FITC, clone MQ1-17H12 is a highly specific rat monoclonal antibody, that targets IL-2 & has been tested in Flow Cytometry, IHC & IP.

    merck millipore,默克密理博,MABF334,Anti-IL-2 (human) Antibody, FITC, clone MQ1-17H12

  • 产品介绍
  • merck millipore,默克密理博,MABF334,Anti-IL-2 (human) Antibody, FITC, clone MQ1-17H12

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, FCRFITCMonoclonal Antibody
    描述
    产品目录编号 MABF334
    描述 Anti-IL-2 (human) Antibody, FITC, clone MQ1-17H12
    Alternate Names
    • IL2
    • Interleukin-2
    • IL-2
    • T-cell growth factor
    • TCGF
    • Aldesleukin
    背景信息 Interleukin-2 (IL-2) is commonly considered a pro-inflammatory cytokine that stimulats T-cell-dependent immune reactions and controls regulatory T cells or Tregs. IL-2 is produced by T-cells in response to antigenic or mitogenic stimulation. IL-2 is required for T-cell proliferation and other activities crucial to regulation of the immune response. Recent studies have shown that IL-2 can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. Structurally, IL-2 is thought to have a 4-helix-bundle-type fold and uses a novel type I cytokine receptor (IL-21R) with the common gamma chain cytokine receptor. IL-2 also may intensify Th1-mediated diseases, including autoimmune arthritis and may also be an interesting clinical target. IL-2 has also been implicated as a possible therapy for infection and cancer. Anti-tumor therapies that include a combination of recombinant IL-2 and recombinant interferon alpha have been promising in clinical studies. Additionally, a chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL).
    产品信息
    格式 FITC
    演示 Purified rat conjugate antibody in buffer containing PBS (pH 7.2) with up to 0.1% sodium azide and 0.2% (w/v) BSA.
    应用
    应用 Anti-IL-2 (human) Antibody, FITC, clone MQ1-17H12 is a highly specific rat monoclonal antibody, that targets IL-2 & has been tested in Flow Cytometry, IHC & IP.
    主要应用
    • Immunohistochemistry
    • Flow Cytometry
    应用说明 Immunohistochemistry Analysis: A representative lot detected human IL-2 in Immunohistochemistry. (Andersson J, et al. 1994; Fernandez V, et al. 1994; Skansen-Saphir U, et al. 1994; Andersson U, et al. Detection and Quantification of Gene Expression; Raqib R, et al. 2002)

    Immunoprecipitation Analysis: A representative lot detected human IL-2 in Immunoprecipitation. (Abrams J, et al. 1992.)
    生物信息
    免疫原品种 E. coli - expressed recombinant human IL-2
    克隆 MQ1-17H12
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rat
    同种型 IgG2aκ
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    基因符号
    • IL2
    纯化方法 Affinity
    UniProt编号
    • P60568
    产品使用声明
    质量保证 The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC and unconjugated antibody.

    Flow Cytometry Analysis: 5 μL of this antibody detected IL-2 in one million PMA/ionomycin-stimulated human peripheral blood lymphocytes.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 The antibody solution should be stored undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
    包装信息
    数量 100 tests

    merck millipore,默克密理博,MABF334,Anti-IL-2 (human) Antibody, FITC, clone MQ1-17H12

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