merck millipore,默克密理愽
  • merck millipore,默克密理博,MABF328,Anti-IL-10 (human) Antibody, PE, clone JES3-19F1

  • merck millipore,默克密理博,MABF328,Anti-IL-10 (human) Antibody, PE, clone JES3-19F1

    产品名称：Anti-IL-10 (human) Antibody, PE, clone JES3-19F1
    产品型号：MABF328
    Anti-IL-10 (human) Antibody, PE, clone JES3-19F1 is a highly specific rat monoclonal antibody & that targets IL-10 & has been tested in Flow Cytometry.

    merck millipore,默克密理博,MABF328,Anti-IL-10 (human) Antibody, PE, clone JES3-19F1

  • 产品介绍
  • merck millipore,默克密理博,MABF328,Anti-IL-10 (human) Antibody, PE, clone JES3-19F1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HFCRPEMonoclonal Antibody
    描述
    产品目录编号 MABF328
    描述 Anti-IL-10 (human) Antibody, PE, clone JES3-19F1
    Alternate Names
    • CSIF
    • Interleukin-10
    • IL-10
    • Cytokine synthesis inhibitory factor
    背景信息 Interleukin-10 (IL-10), originally known as Cytokine Synthesis Inhibitory Factor (CSIF) is a protein that shares over 80% sequence homology with the Epstein-Barr Virus protein BCRFI. IL-10 down regulates the expression of Th1 cytokines, major histocompatibility complex class II antigens, and costimulatory molecules on macrophages. It also enhaces B cell survival, proliferation, and antibody production. IL-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. IL-10 is produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types. A polymorphism in IL10 promoter region is associated with resistance to graft-versus-host disease (GVHDS), a major complication of allogeneic bone marrow transplantation, in which mature donor T-cells that contaminate the allogeneic bone marrow recognize the tissues of the recipient as foreign, causing a severe inflammatory disease. Knockout studies suggest that IL-10 is an immunoregulator in the intestinal tract.
    产品信息
    格式 PE
    演示 Purified rat conjugate antibody in buffer containing PBS (pH 7.2) with up to 0.1% sodium azide and 0.2% (w/v) BSA.
    应用
    应用 Anti-IL-10 (human) Antibody, PE, clone JES3-19F1 is a highly specific rat monoclonal antibody & that targets IL-10 & has been tested in Flow Cytometry.
    主要应用
    • Flow Cytometry
    生物信息
    免疫原品种 COS-expressed recombinant human IL-10
    克隆 JES3-19F1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rat
    同种型 IgG2aκ
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    基因符号
    • IL10
    纯化方法 Affinity
    UniProt编号
    • P22301
    产品使用声明
    质量保证 The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    Flow Cytometry Analysis: 20 μL of this antibody detected IL-10 in one million LPS-stimulated human peripheral blood monocytes.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 The antibody solution should be stored undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
    包装信息
    数量 100 tests

    merck millipore,默克密理博,MABF328,Anti-IL-10 (human) Antibody, PE, clone JES3-19F1

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