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merck millipore,默克密理博,MABE982,Anti-RBP-Jk, clone 1F1 Antibody
产品名称:Anti-RBP-Jk, clone 1F1 Antibody
产品型号:MABE982
This Anti-RBP-Jk, clone 1F1 Antibody is validated for use in Immunoprecipitation and Chromatin Immunoprecipitation (ChIP) and Electrophoretic Mobility Shift Assay for the detection of RBP-Jk.
merck millipore,默克密理博,MABE982,Anti-RBP-Jk, clone 1F1 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Dr, H EMSA, ChIP R Purified Monoclonal Antibody 描述 产品目录编号 MABE982 描述 Anti-RBP-Jk, clone 1F1 Antibody Alternate Names - Renal carcinoma antigen NY-REN-30
- Recombining binding protein suppressor of hairless
- CBF-1
- J kappa-recombination signal-binding protein
- RBP-J kappa
- RBP-J
- RBP-JK
背景信息 RBP-jk, Recombinant signal binding protein for immunoglobin kappa J region, is a human homolog for the Drosophila gene, suppressor of hairless. RBP-jk is located in the nucleus and is a 60 kDa monomeric protein that is used as a promoter region in notch signaling. Notch signaling is important in cell to cell communication which allows "a differentiating cell to suppress the same differentiation fate in a neighboring cell (the receiving cell). This ensures that the correct number of cells are distributed to distinct cell fates." When RBP-jk is not associated with Notch proteins, it acts as a transcriptional repressor. A disease associated with RBP-jk is the Epstein Barr virus. 产品信息 格式 Purified 演示 Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-RBP-Jk, clone 1F1 Antibody is validated for use in Immunoprecipitation and Chromatin Immunoprecipitation (ChIP) and Electrophoretic Mobility Shift Assay for the detection of RBP-Jk. 主要应用 - Electrophoretic Mobility Shift Assay
- Chromatin Immunoprecipitation (ChIP)
应用说明 Chromatin Immunoprecipitation Analysis: A representative lot immunoprecipitated RBP-Jk using Hippocampal NSC's (Ehm, O., et al. (2010). Journal of Neuroscience. 30(41):13794-18707).
Electrophoretic Mobility Shift Assay: A representative lot detected RBP-Jk using Hippocampal lysate (Ehm, O., et al. (2010). Journal of Neuroscience. 30(41):13794-18707).
Chromatin Immunoprecipitation Analysis: A representative lot immunoprecipitated RBP-Jk using Lymphoblastoid cell line.
Immunoprecipitation Analysis: A representative lot immunoprecipitated RBP-Jk using DG75 cells.生物信息 免疫原品种 Recombinant protein corresponding to human RBP-Jk. 克隆 1F1 浓缩 Please refer to lot specific datasheet. 宿主 Rat 同种型 IgG2aκ 品种反应性 DrosophilaHuman 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_005340
基因符号 - RBPSUH
- RBPJ
- IGKJRB
- IGKJRB1
- RBPJK
纯化方法 Protein G purified UniProt编号 - Q06330 (Human)
产品使用声明 质量保证 Evaluated by Immunoprecipitation in HeLa cell lysate.
Immunoprecipitation Analysis: 10 µg of this antibody immunoprecipitated RBP-Jk in 0.5 mg of HeLa cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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