merck millipore,默克密理博,MABE582,Anti-phospho-Cyclin E1 (Thr77), clone EPR2242(2), Rabbit Monoclonal Antibody

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merck millipore,默克密理博,MABE582,Anti-phospho-Cyclin E1 (Thr77), clone EPR2242(2), Rabbit Monoclonal Antibody
产品名称：Anti-phospho-Cyclin E1 (Thr77), clone EPR2242(2), Rabbit Monoclonal Antibody
产品型号：MABE582
This Anti-phospho-Cyclin E1 (Thr77), clone EPR2242(2), Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of phospho-Cyclin E1 (Thr77).

merck millipore,默克密理博,MABE582,Anti-phospho-Cyclin E1 (Thr77), clone EPR2242(2), Rabbit Monoclonal Antibody

产品介绍

merck millipore,默克密理博,MABE582,Anti-phospho-Cyclin E1 (Thr77), clone EPR2242(2), Rabbit Monoclonal Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	IHC, WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABE582
描述	Anti-phospho-Cyclin E1 (Thr77), clone EPR2242(2), Rabbit Monoclonal Antibody
Alternate Names	G1/S-specific cyclin-E1
背景信息	G1/S-specific cyclin-E1 (CCNE1), also known as Cyclin E1, is a member of the cyclin E family that can associate with and activate cyclin-dependent kinase Cdk2. Expression of cyclin E1 is essential for the control of the cell cycle at the late G1 and early S phase. The cyclin E/Cdk2 complex plays an essential and limiting role in the transition between G1 and S phase as well as the initiation of DNA replication Ubiquination by the Cul-3 pathway and by Fbw7 regulates cyclin E1 levels and is critically important in normal cells. Abnormally high levels of cyclin E expression have frequently been observed in human cancers. Moreover, high cyclin E1 levels correlate with increased tumor aggression and poor prognosis.

产品信息
格式	Unpurified
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	This Anti-phospho-Cyclin E1 (Thr77), clone EPR2242(2), Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of phospho-Cyclin E1 (Thr77).
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:100-250 dilution from a representative lot detected phospho-Cyclin E1 (Thr77) in human colon tissue. Produced in collaboration with Epitomics™

生物信息
免疫原品种	Synthetic peptide corresponding to human phospho-Cyclin E1 (Thr77).
克隆	EPR2242(2)
浓缩	Please refer to lot specific datasheet.
宿主	Rabbit
同种型	IgG
品种反应性	Human
Species Reactivity Note	Human
抗体类型	Monoclonal Antibody
基因符号	CCNE CCNE1
纯化方法	Unpurified
UniProt编号	P24864

产品使用声明
质量保证	Evaluated by Western Blotting in JAR untreated and JAR treated with Lambda Phosphatase cell lysates. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected phospho-Cyclin E1 (Thr77) in JAR untreated and JAR treated with Lambda Phosphatase cell lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.