merck millipore,默克密理博,MABE194,Anti-WSTF Antibody, clone EP1704Y, rabbit monoclonal

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merck millipore,默克密理博,MABE194,Anti-WSTF Antibody, clone EP1704Y, rabbit monoclonal
产品名称：Anti-WSTF Antibody, clone EP1704Y, rabbit monoclonal
产品型号：MABE194
Use Anti-WSTF Antibody, clone EP1704Y (Rabbit Monoclonal Antibody) validated in WB, FC, IHC(P), ICC to detect WSTF also known as Williams-Beuren syndrome chromosomal region 10 protein.

merck millipore,默克密理博,MABE194,Anti-WSTF Antibody, clone EP1704Y, rabbit monoclonal

产品介绍

merck millipore,默克密理博,MABE194,Anti-WSTF Antibody, clone EP1704Y, rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	ICC, WB, FC	Rb	Diluted Culture Supernatant	Monoclonal Antibody

描述
产品目录编号	MABE194
描述	Anti-WSTF Antibody, clone EP1704Y, rabbit monoclonal
Alternate Names	Bromodomain adjacent to zinc finger domain protein 1B bromodomain adjacent to zinc finger domain, 1B Williams-Beuren syndrome chromosomal region 10 protein Williams-Beuren syndrome chromosomal region 9 protein Williams syndrome transcription factor transcription factor WSTF tyrosine-protein kinase BAZ1B
背景信息	The Williams Syndrome Transcription Factor (WSTF), the product of the WBSCR9 gene, is invariably deleted in the haploinsufficiency Williams-Beuren Syndrome. Along with the nucleosome-dependent ATPase ISWI, WSTF forms a novel chromatin remodeling complex, WICH (WSTFISWI chromatin remodeling complex). WSTF binds stably to mitotic chromosomes. As dysfunction of other chromatin remodeling factors often has severe effects on development, haploinsufficiency of WSTF may explain some of the phenotypes associated with this disease (1). Evidence has shown that the WSTF is targeted to replication foci through direct interaction with the DNA clamp PCNA, an important coordinator of DNA and chromatin replication. WSTF, in turn, recruits ISWI-type nucleosome-remodelling factor SNF2H to replication sites. It has been proposed that the WSTF-ISWI complex has a role in the maintenance of chromatin structures during DNA replication (2).

产品信息
格式	Diluted Culture Supernatant
控制	HeLa cell lysate
演示	Rabbit Monoclonal in buffer containing 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl containing 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

应用
应用	Use Anti-WSTF Antibody, clone EP1704Y (Rabbit Monoclonal Antibody) validated in WB, FC, IHC(P), ICC to detect WSTF also known as Williams-Beuren syndrome chromosomal region 10 protein.
主要应用	Immunocytochemistry Western Blotting Flow Cytometry
应用说明	Flow Cytometry Analysis: 1:20 dilution from a representative lot was used in FC. Immunohistochemistry Analysis: 1:50-1:100 dilution from a representative lot detected WSTF in human lymphoma tissue. Immunocytochemistry Analysis: 1:100-250 dilution from a representative lot detected WSTF in HeLa cells.

生物信息
免疫原品种	Synthetic peptide corresponding to human WSTF near the C-terminus.
表位	Near C-terminus
克隆	EP1704Y
宿主	Rabbit
特异性	This antibody recognizes WSTF near the C-terminus.
同种型	IgG
品种反应性	RatHumanMouse
Species Reactivity Note	Demonstrated to react with Human, Mouse, and Rat.
抗体类型	Monoclonal Antibody
基因符号	EC 2.7.10.2 WSTF WBSCR9 hWALp2 WBSCR10 OTTHUMP00000197535 WBSC10
纯化方法	Unpurified
UniProt编号	Q9UIG0

产品使用声明
质量保证	Evaluated by Western Blot in HeLa cell lysate. Western Blot Analysis: 1:500 dilution of this antibody detected WSTF in HeLa cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing Solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below
-20°C may cause glycerol containing Solutions to become frozen during storage.