merck millipore,默克密理愽
  • merck millipore,默克密理博,672315,Ursolic Acid - CAS 77-52-1 - Calbiochem

  • merck millipore,默克密理博,672315,Ursolic Acid - CAS 77-52-1 - Calbiochem

    产品名称：Ursolic Acid - CAS 77-52-1 - Calbiochem
    产品型号：672315
    A cell-permeable plant-derived pentacyclic triterpene acid that displays anti-inflammatory, immunomodulatory, and antitumor activities.

    merck millipore,默克密理博,672315,Ursolic Acid - CAS 77-52-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,672315,Ursolic Acid - CAS 77-52-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₃₀H₄₈O₃77-52-1
    描述
    概述 A cell-permeable plant-derived pentacyclic triterpene acid that displays anti-inflammatory, immunomodulatory, and antitumor activities. Shown to inhibit the phosphatase activity of SHP2, PTP1B, and TCPTP (IC50 = 2.73, 3.08 and 3.33 µM, respectively) as well as induce IR autophosphorylation independent of its phosphatase inhibitory activity. Ursolic acid is also reported to inhibit NF-κB and STAT3 pathway activation in cancer cultures, resulting in enhanced sensitivity to chemotherapy agents and apoptotic cell death.
    产品目录编号 672315
    品牌系列 Calbiochem®
    同义词 3β-Hydroxy-urs-12-en-28-oic acid, CG7, PTPN2/TCPTP Inhibitor II, SHP2 Inhibitor IV, PTP1B Inhibitor VII, PTP Inhibitor XXVII
    参考
    参考 Li, Y., et al. 2010. Int. J. Cancer 127, 462.
    Pathak, A.K., et al. 2007. Mol. Cancer Res. 5, 943.
    Jung, S.H., et al. 2007. Biochem. J. 403, 243.
    Zhang, W., et al. 2006. Biochim. Biophys. Acta 1760, 1505.
    Shishodia, S., et al. 2003. Cancer Res. 63, 4375.
    产品信息
    CAS号 77-52-1
    形式 White powder
    Hill配方 C₃₀H₄₈O₃
    化学配方 C₃₀H₄₈O₃
    Molar Mass 456.7
    结构配方图像
    生物信息
    纯度 ≥98% by HPLC
    理化信息
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,672315,Ursolic Acid - CAS 77-52-1 - Calbiochem

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