merck millipore,默克密理愽
  • merck millipore,默克密理博,MABE164,Anti-ID4 Antibody, clone DML07

  • merck millipore,默克密理博,MABE164,Anti-ID4 Antibody, clone DML07

    产品名称：Anti-ID4 Antibody, clone DML07
    产品型号：MABE164
    Use Anti-ID4 Antibody, clone DML07 (Mouse Monoclonal Antibody) validated in WB to detect ID4 also known as DNA-binding protein inhibitor ID-4, Class B basic helix-loop-helix protein 27, bHLHb27.

    merck millipore,默克密理博,MABE164,Anti-ID4 Antibody, clone DML07

  • 产品介绍
  • merck millipore,默克密理博,MABE164,Anti-ID4 Antibody, clone DML07

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HWBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABE164
    描述 Anti-ID4 Antibody, clone DML07
    Alternate Names
    • Inhibitor of DNA binding 4
    • DNA-binding protein inhibitor ID-4
    • Class B basic helix-loop-helix protein 27
    • bHLHb27
    背景信息 ID4 is an inhibitor of differentiation protein, which, along with ID1, ID2 and ID3, plays a key role in the regulation of lineage commitment, cell fate decisions and in the timing of differentiation during neurogenesis, lymphopoiesis and neovascularisation (angiogenesis). ID proteins, induced by the bone morphogenic protein-SMAD pathway, have also been shown to cooperate with LIF to ensure that embryonic stem cells opt for self-renewal.
    产品信息
    格式 Purified
    控制
    • Human lung tissue lysate
    演示 Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Use Anti-ID4 Antibody, clone DML07 (Mouse Monoclonal Antibody) validated in WB to detect ID4 also known as DNA-binding protein inhibitor ID-4, Class B basic helix-loop-helix protein 27, bHLHb27.
    主要应用
    • Western Blotting
    应用说明 Western Blot Analysis: 1 µg/mL from a representative lot detected ID4 on 10 µg of mouse lymph node tissue lysate.
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to human ID4.
    克隆 DML07
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG2bκ
    品种反应性 MouseHuman
    Species Reactivity Note Demonstrated to react with Human and Mouse.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_001537
    Entrez基因汇总 Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins (Pagliuca et al., 1995 [PubMed 7665172]).[supplied by OMIM].
    基因符号
    • ID4
    纯化方法 Protein G purified
    UniProt编号
    • P47928
    UniProt汇总 FUNCTION: ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding.

    SUBUNIT STRUCTURE: Heterodimer with other HLH proteins.

    SUBCELLULAR LOCATION: Nucleus.

    SEQUENCE SIMILARITIES: Contains 1 basic helix-loop-helix (bHLH) domain.
    产品使用声明
    质量保证 Evaluated by Western Blot in human lung tissue lysate.

    Western Blot Analysis: 1 µg/mL of this antibody detected ID4 on 10 µg of human lung tissue lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABE164,Anti-ID4 Antibody, clone DML07

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下一件merck millipore产品：merck millipore,默克密理博,NB20,Anti-AnkyrinG Mouse mAb (463)


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