merck millipore,默克密理愽
  • merck millipore,默克密理博,MABE163,Anti-ASF-1 (SF2) Antibody, clone AK96

  • merck millipore,默克密理博,MABE163,Anti-ASF-1 (SF2) Antibody, clone AK96

    产品名称：Anti-ASF-1 (SF2) Antibody, clone AK96
    产品型号：MABE163
    Use Anti-ASF-1 (SF2) Antibody, clone AK96 (mouse monoclonal antibody) validated in WB, IP, ICC, IHC to detect ASF-1 (SF2) also known as splicing factor arginine/serine-rich 1, Alternative-splicing fac More>>

    merck millipore,默克密理博,MABE163,Anti-ASF-1 (SF2) Antibody, clone AK96

  • 产品介绍
  • merck millipore,默克密理博,MABE163,Anti-ASF-1 (SF2) Antibody, clone AK96

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABE163
    Replaces MABE512
    描述 Anti-ASF-1 (SF2) Antibody, clone AK96
    Alternate Names
    • SF2
    • splicing factor, arginine/serine-rich 1
    • Alternative-splicing factor 1
    • pre-mRNA-splicing factor SF2, P33 subunit
    • splicing factor 22
    • ASF-1
    背景信息 Alternative-splicing factor 1 (ASF-1), also known as SRp30a or SF2, is a member of the highly conserved family of SR proteins, a group of serine/arginine-rich domain-containing proteins that play a critical role in regulated and constitutive splicing of precursor mRNA. The SR family of proteins is characterized as having one to two RNA recognition motifs located in the n-terminal sequence, and an RS domain within the C-terminus that is rich in serine/arginine dipeptide repeats. ASF-1 has an inhibitory role in exon skipping, in order to maintain splicing accuracy and to monitor alternative splicing. Studies have shown that ASF-1 plays a role in the regulation of caspase-9 alternative splicing as well as being a critical component for ceramide to function as a mediator of alternative splicing for the same caspase.
    产品信息
    格式 Purified
    控制
    • Human lymph node lysate
    演示 Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl without 0.05% sodium azide.
    应用
    应用 Use Anti-ASF-1 (SF2) Antibody, clone AK96 (mouse monoclonal antibody) validated in WB, IP, ICC, IHC to detect ASF-1 (SF2) also known as splicing factor arginine/serine-rich 1, Alternative-splicing factor 1 & pre-mRNA-splicing factor SF2 P33 subunit
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected ASF-1 (SF2) in human prostate carcinoma cells and human testis tissue.
    Western Blotting Analysis: A representative lot was used by an independent laboratory in western blotting (Sinha, R., et al. (2010). Mol. Cell. Biol. doi:10.1128/MCB.01270-09).
    Immunoprecipitation Analysis: A representative lot immunoprecipitated ASF-1 (SF2) in HeLa nuclear extracts (Jablonski, J. A., et al. (2010). Nucleic Acids Research. 38(4):1249-1260).
    生物信息
    免疫原品种 MBP-tagged recombinant protein corresponding to the N-terminus of human ASF-1 (SF2).
    表位 N-terminus
    克隆 AK96
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 This antibody recognizes the N-terminus of ASF-1 (SF2).
    同种型 IgG2aκ
    品种反应性 Human
    Species Reactivity Note Demonstrated to react with Human. Immunogen sequence is identical in mouse and rat, so reactivity is predicted.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_001071634
    Entrez基因汇总 This gene encodes a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
    基因符号
    • SRp30a
    • SF2
    • ASF
    • ASF-1
    • SF2p33
    • SF2P33
    纯化方法 Protein G purified
    UniProt编号
    • Q07955
    产品使用声明
    质量保证 Evaluated by Western Blot in human lymph node lysate.

    Western Blot Analysis: 0.5 µg/mL of this antibody detected ASF-1 (SF2) on 10 µg of human lymph node lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABE163,Anti-ASF-1 (SF2) Antibody, clone AK96

上一件merck millipore产品：merck millipore,默克密理博,SF-2476,GABRB3; Human, Cyanine 5 RNA Detection Probe,SmartFlare
下一件merck millipore产品：merck millipore,默克密理博,521726,Platelet Factor 4, Human Platelets


相关产品

merck millipore,默克密理博,AB764P,Anti-Procollagen Type III PIIINP Antibody merck millipore,默克密理博,AB764P,Anti-Procollagen Type III PIIINP Antibody

merck millipore,默克密理博,MABF715,Anti-CD62L (L-Selectin) Antibody (mouse), APC, clone MEL-14 merck millipore,默克密理博,MABF715,Anti-CD62L (L-Selectin) Antibody (mouse), APC, clone MEL-14

merck millipore,默克密理博,ABT115,Anti-FucT-III Antibody merck millipore,默克密理博,ABT115,Anti-FucT-III Antibody

merck millipore,默克密理博,SF-116,EGFR; Mouse, Cyanine 5, RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-116,EGFR; Mouse, Cyanine 5, RNA Detection Probe,SmartFlare

merck millipore,默克密理博,SF-2476,GABRB3; Human, Cyanine 5 RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-2476,GABRB3; Human, Cyanine 5 RNA Detection Probe,SmartFlare

merck millipore,默克密理博,521726,Platelet Factor 4, Human Platelets merck millipore,默克密理博,521726,Platelet Factor 4, Human Platelets

merck millipore,默克密理博,475986,mTOR Kinase Inhibitor II, WYE-354 - CAS 1062169-56-5 - Calbiochem merck millipore,默克密理博,475986,mTOR Kinase Inhibitor II, WYE-354 - CAS 1062169-56-5 - Calbiochem

merck millipore,默克密理博,SCR013,LT2 Immortalized Pancreatic Mesenchymal Cell Line merck millipore,默克密理博,SCR013,LT2 Immortalized Pancreatic Mesenchymal Cell Line

merck millipore,默克密理博,ABN117,Anti-PDE4D3 Antibody merck millipore,默克密理博,ABN117,Anti-PDE4D3 Antibody

merck millipore,默克密理博,14-790M,PI3 Kinase (p110α/p65α), 250 µg merck millipore,默克密理博,14-790M,PI3 Kinase (p110α/p65α), 250 µg


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部