merck millipore,默克密理博,MABD188,Anti-BMP4, clone EPR6211, Rabbit Monoclonal Antibody

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

当前位置：首页 > >Merck Millipore > 生命科学研究
生命科学研究

merck millipore,默克密理博,MABD188,Anti-BMP4, clone EPR6211, Rabbit Monoclonal Antibody
产品名称：Anti-BMP4, clone EPR6211, Rabbit Monoclonal Antibody
产品型号：MABD188
This Anti-BMP4, clone EPR6211, Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of BMP4.

merck millipore,默克密理博,MABD188,Anti-BMP4, clone EPR6211, Rabbit Monoclonal Antibody

产品介绍

merck millipore,默克密理博,MABD188,Anti-BMP4, clone EPR6211, Rabbit Monoclonal Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	IHC, WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABD188
描述	Anti-BMP4, clone EPR6211, Rabbit Monoclonal Antibody
Alternate Names	BMP-2B Bone morphogenetic protein 4 BMP-4 Bone morphogenetic protein 2B
背景信息	Bone morphogenetic protein 4 (BMP4) is a polypeptide belonging to the TGF-β superfamily of proteins. It, like other bone morphogenetic proteins, is involved in bone and cartilage development, specifically tooth and limb development and fracture repair. It has been shown to be involved in muscle development, bone mineralization, and uteric bud development. BMP4 has also been implicated in Fibrodysplasia Ossificans Progressiva in which it is underexpressed. In human embryonic development, BMP4 is a critical signalling molecule required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. BMP4 is secreted from the dorsal portion of the notochord, and it acts in concert with sonic hedgehog (released from the ventral portion of the notochord) to establish a dorsal-ventral axis for the differentiation of later structures. BMP4 stimulates differentiation of overlying ectodermal tissue. Inhibition of the BMP4 signal (by chordin, noggin, or follistatin) causes the ectoderm to differentiate into the neural plate. If these cells also receive signals from FGF, they will differentiate into the spinal cord; in the absence of FGF the cells become brain tissue.

产品信息
格式	Unpurified
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	This Anti-BMP4, clone EPR6211, Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of BMP4.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:100-250 dilution from a representative lot detected BMP4 in human colon tissue. Produced in collaboration with Epitomics™

生物信息
免疫原品种	Synthetic peptide corresponding to human BMP4.
克隆	EPR6211
浓缩	Please refer to lot specific datasheet.
宿主	Rabbit
同种型	IgG
品种反应性	Human
Species Reactivity Note	Human
抗体类型	Monoclonal Antibody
基因符号	DVR4 BMP4 BMP2B
纯化方法	Unpurified
UniProt编号	P12644

产品使用声明
质量保证	Evaluated by Western Blotting in human fetal liver, A549, HeLa, A431, and human heart lysates. Western Blotting Analysis: A 1:10,000-50,000 dilution of this antibody detected BMP4 in human fetal liver, A549, HeLa, A431, and human heart lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.