merck millipore,默克密理博,MABD167,Anti-GATA1 Antibody, clone 4F5

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	IHC, WB, ICC	M	Ascites	Monoclonal Antibody

描述
产品目录编号	MABD167
Replaces	MABE470
描述	Anti-GATA1 Antibody, clone 4F5
Alternate Names	NF-E1 DNA-binding protein Erythroid transcription factor Eryf1 GATA-binding factor 1 GATA-1 GF-1
背景信息	GATA-1 (GATA1), or alternatively Gata-binding factor 1, GF-1, NF-E1 DNA binding protein, and Erythroid transcription factor (EryF1) encoded by the human gene named GATA1/ERYF1/GF1 is transcriptional activator central for erythroid development. GATA1 also plays critical roles in controlling gene expression in other system as well. Research has shown that GATA1 contributes to the level of alpha synuclein gene expression in Parkinson’s disease and over expression of GATA1 in cortical neurons leads to a decrease in the expression of Rab4b and reduces dendrite branching and maturation, and GATA1 expression is elevated in brains with depressive disorder suggesting that GATA1 may be new target for anti-depressant therapies. EMD-Millipore’s Anti-GATA1 mouse monoclonal antibody has been tested in western blot on K562 cell lysates and paraffin embedded immunohistochemistry on pancreatic cancer tissues and in fluorescent immunocytochemistry on K562 cells in culture.

产品信息
格式	Ascites
控制	K562 cell lysate
演示	Mouse monoclonal IgG2b ascitic fluid containing up to 0.1% sodium azide.

应用
应用	Anti-GATA1 Antibody, clone 4F5 is a highly specific mouse monoclonal antibody, that targets GATA & has been tested in western blotting, ICC & IHC.
主要应用	Immunohistochemistry Western Blotting Immunocytochemistry
应用说明	Immunofluorescence Analysis: A 1:200-1,000 dilution from a representative lot detected GATA1 in K562 cells. Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected GATA1 in pancreatic cancer tissue. Optimal working dilutions must be determined by end user.

生物信息
免疫原品种	Purified recombinant fragment of human GATA1 expressed in E. Coli.
克隆	4F5
宿主	Mouse
同种型	IgG2b
品种反应性	Human
抗体类型	Monoclonal Antibody
基因符号	GATA1 GF1 GF-1 NFE1 XLTT ERYF1 GATA-1
纯化方法	Unpurified
UniProt编号	P15976

产品使用声明
质量保证	Evaluated by Western Blotting in K562 cell lysate. Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected GATA1 in K562 cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

包装信息
数量	100 µL

merck millipore,默克密理博,MABD167,Anti-GATA1 Antibody, clone 4F5

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