merck millipore,默克密理博,MABD116,Anti-Dux4 Antibody, clone 9A12

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	EMSA, WB, ICC	M	Purified	Monoclonal Antibody

描述
产品目录编号	MABD116
描述	Anti-Dux4 Antibody, clone 9A12
Alternate Names	Dux-4 double homeobox protein 4 Double homeobox protein 10 Double homeobox protein 4/10
背景信息	Dux4 is a homeodomain protein with a similar protein sequence to Pax3 and Pax7. Defects in Dux4 may be the cause of facioscapulohumeral muscular dystrophy (FSHD). FSHD is characterized by weakness of the muscles of the face, upper-arm and shoulder girdle. Ectopic expression of Dux4 in skeletal muscle activates the expression of stem cell and germline genes, and, when overexpressed in somatic cells, Dux4 can ultimately lead to cell death.

产品信息
格式	Purified
控制	Human skeletal muscle tissue lysate.
演示	Purified mouse monoclonal IgG1κ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	Detect Dux4 using this mouse monoclonal antibody, Anti-Dux4 Antibody, clone 9A12 validated for use in western blotting, ICC, Electrophoretic Mobility Shift Assay & IP.
主要应用	Electrophoretic Mobility Shift Assay Western Blotting Immunocytochemistry
应用说明	This antibody has been shown to work in immunocytochemistry applications (Dixit et al. 2007). This antibody has been shown to work in electrophoretic mobility shift assays (Dixit et al. 2007). This antibody has been shown to work in immunoprecipitation applications (Anseau et al., 2009).

生物信息
免疫原品种	recombinant protein corresponding to the domain of: C-Terminal region of Human Dux4.
表位	domain of: C-Terminal region
克隆	9A12
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
同种型	IgG1κ
品种反应性	Human
Species Reactivity Note	Human.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_149418
基因符号	DUX10 DUX4
纯化方法	Protein G purified
UniProt编号	Q9UBX2

产品使用声明
质量保证	Evaluated by Western Blot in a human skeletal muscle tissue lysate. Western Blot Analysis: A 1:250 dilution of this antibody detected Dux4 in a human skeletal muscle tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µL

merck millipore,默克密理博,MABD116,Anti-Dux4 Antibody, clone 9A12

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