merck millipore,默克密理博,MABC775,Anti-PLAU, clone EPR6273, Rabbit Monoclonal Antibody

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merck millipore,默克密理博,MABC775,Anti-PLAU, clone EPR6273, Rabbit Monoclonal Antibody
产品名称：Anti-PLAU, clone EPR6273, Rabbit Monoclonal Antibody
产品型号：MABC775
This Anti-PLAU, clone EPR6273, Rabbit Monoclonal Antibody is validated for use in Western Blotting and Flow Cytometry for the detection of PLAU.

merck millipore,默克密理博,MABC775,Anti-PLAU, clone EPR6273, Rabbit Monoclonal Antibody

产品介绍

merck millipore,默克密理博,MABC775,Anti-PLAU, clone EPR6273, Rabbit Monoclonal Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	FC, WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABC775
描述	Anti-PLAU, clone EPR6273, Rabbit Monoclonal Antibody
Alternate Names	uPA Urokinase-type plasminogen activator U-plasminogen activator
背景信息	Urokinase-type plasminogen activator (U-plasminogen activator or uPA), and encoded by the gene name PLAU, is a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific mutation in PLAU may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. It converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor.

产品信息
格式	Unpurified
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	This Anti-PLAU, clone EPR6273, Rabbit Monoclonal Antibody is validated for use in Western Blotting and Flow Cytometry for the detection of PLAU.
主要应用	Flow Cytometry Western Blotting
应用说明	Flow Cytometry Analysis: A 1:100-500 dilution from a representative lot detected PLAU in MCF7 cells. Produced in collaboration with Epitomics™

生物信息
免疫原品种	Synthetic peptide corresponding to human PLAU.
克隆	EPR6273
浓缩	Please refer to lot specific datasheet.
宿主	Rabbit
同种型	IgG
品种反应性	Human
Species Reactivity Note	Human
抗体类型	Monoclonal Antibody
基因符号	PLAU
纯化方法	Unpurified
UniProt编号	P00749

产品使用声明
质量保证	Evaluated by Western Blotting in PC3, LNCaP and MCF7 cell lysates. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected PLAU in PC3, LNCaP and MCF7 cell lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.