merck millipore,默克密理博,MABC743,Anti-Cytochrome C, clone EPR1327, Rabbit Monoclonal Antibody

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merck millipore,默克密理博,MABC743,Anti-Cytochrome C, clone EPR1327, Rabbit Monoclonal Antibody
产品名称：Anti-Cytochrome C, clone EPR1327, Rabbit Monoclonal Antibody
产品型号：MABC743
This Anti-Cytochrome C, clone EPR1327, Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunohistochemistry and Immunofluorescence for the detection of Cytochrome C.

merck millipore,默克密理博,MABC743,Anti-Cytochrome C, clone EPR1327, Rabbit Monoclonal Antibody

产品介绍

merck millipore,默克密理博,MABC743,Anti-Cytochrome C, clone EPR1327, Rabbit Monoclonal Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	IHC, WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABC743
Replaces	04-1043
描述	Anti-Cytochrome C, clone EPR1327, Rabbit Monoclonal Antibody
Alternate Names	Cytochrome c
背景信息	Cytochrome c (CYCS) is located in the mitochondria of all aerobic cells and is involved in the electron transport system that functions in oxidative phosphorylation. It accepts electrons from cytochrome b and transfers them to cytochrome oxidase. In the process, the iron of the heme group, which is identical to that of hemoglobin and myoglobin, shifts from the ferrous to the ferric state. Recent progress in studies on apoptosis has revealed that cytochrome c is a pro-apoptotic factor. It is released from its places on the outer surface of the inner mitochondrial membrane at early steps of apoptosis and, combining with some cytosolic proteins, activates conversion of the latent apoptosis-promoting protease pro-caspase-9 to its active form. Cytochrome c release can be initiated by the pro-apoptotic protein Bax. This process is blocked by the anti-apoptotic proteins Bcl-2 and Bcl-xL. Also, differences in amino acid composition of cytochrome c have also been used as markers of biochemical evolution.

产品信息
格式	Unpurified
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	This Anti-Cytochrome C, clone EPR1327, Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunohistochemistry and Immunofluorescence for the detection of Cytochrome C.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:250-500 dilution from a representative lot detected Cytochrome C in human kidney tissue. Immunofluorescence Analysis: A 1:100-250 dilution from a representative lot detected Cytochrome C in HeLa cells. Produced in collaboration with Epitomics™

生物信息
免疫原品种	Synthetic peptide corresponding to human Cytochrome C.
克隆	EPR1327
浓缩	Please refer to lot specific datasheet.
宿主	Rabbit
同种型	IgG
品种反应性	Human
Species Reactivity Note	Human
抗体类型	Monoclonal Antibody
基因符号	CYC CYCS
纯化方法	Unpurified
UniProt编号	P99999

产品使用声明
质量保证	Evaluated by Western Blotting in Molt4, SH-SY5Y, human heart, human kidney and human spleen lysates. Western Blotting Analysis: A 1:10,000-50,000 dilution of this antibody detected Cytochrome C in Molt4, SH-SY5Y, human heart, human kidney and human spleen lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.