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merck millipore,默克密理博,MABC192,Anti-Caspase 10 Antibody, clone 16C5.1
产品名称:Anti-Caspase 10 Antibody, clone 16C5.1
产品型号:MABC192
Detect Caspase 10 using this mouse monoclonal antibody, Anti-Caspase 10 Antibody, clone 16C5.1 validated for use in western blotting & IHC.
merck millipore,默克密理博,MABC192,Anti-Caspase 10 Antibody, clone 16C5.1
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H, R IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABC192 描述 Anti-Caspase 10 Antibody, clone 16C5.1 Alternate Names - Caspase-10 subunit p12
- Caspase-10
- CASP-10
- Apoptotic protease Mch-4
- FAS-associated death domain protein interleukin-1B-converting enzyme 2
- FLICE2
- ICE-like apoptotic protease 4
- Caspase-10 subunit p23/17
背景信息 Caspase-10 is a member of the peptidase C14A family and is involved in the activation cascade of caspases responsible for apoptosis execution. Caspase-10 has two death effector domains (DEDs) that bind to the DED in the adapter molecule FADD and recruits both TNFR1 and CD95 to form complexes with these receptors. Caspase-10 is expressed in many tissues and cell lines with the lowest expression found in brain, kidney, prostate, testis, and colon. Mutations in Caspase-10 have been associated with autoimmune lymphoproliferative syndrome type 2A and gastric cancer. 产品信息 格式 Purified 演示 Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect Caspase 10 using this mouse monoclonal antibody, Anti-Caspase 10 Antibody, clone 16C5.1 validated for use in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western Blotting Analysis: 1.0 µg/mL from a representative lot detected Caspase 10 in 10 µg of rat and mouse kidney tissue lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Caspase 10 in human prostate cancer sections.生物信息 免疫原品种 GST-tagged recombinant protein corresponding to the caspase 10 subunit p23/17 of human Caspase 10. 表位 Caspase 10 subunit p23/17 克隆 16C5.1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG2bκ 品种反应性 MouseHumanRat Species Reactivity Note Human, Rat, Mouse. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_001193453
基因符号 - MCH4
- CASP10
纯化方法 Protein G purified UniProt编号 - Q92851
产品使用声明 质量保证 Evaluated by Western Blotting in K562 cell lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected Caspase 10 in 10 µg of K562 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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