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品种反应性 主要应用 宿主 格式 抗体类型 Human Only IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MAB5622 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Secretagogin Antibody 产品信息 格式 Purified 演示 Liquid in PBS with 0.1% sodium azide. 应用 应用 Anti-Secretagogin Antibody is an antibody against Secretagogin for use in WB, IH. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western blot: 1:500-1:1,000 on human cerebellum.
Immunohistochemistry on human brain tissue fixed in acetone.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Human insulinoma. 克隆 D24 宿主 Mouse 特异性 Secretagogin. The monoclonal recognizes a 32 kDa protein on immunoblot analysis of neuroendocrine tumor cells and human cerebellum. By immunohistochemistry it reacts with normal pancreatic beta-cells and tumors such as vipoma, gastrinoma and carcinoid. No reactivity seen by immunohistochemistry on exocrine pancreatic tissue. 同种型 IgG 品种反应性 Human Only Species Reactivity Note Human. No reactivity with rodent beta cells or a canine insulinoma. 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_006998.3
Entrez基因汇总 The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in KCL-stimulated calcium flux and cell proliferation. 基因符号 - Secretagogin.
- SCGN
- DJ501N12.8
- setagin
- secretagogin
- SECRET
- CALBL
- SEGN
- calbindin-like
UniProt编号 - O76038
UniProt汇总 SIZE: 276 amino acids; 32040 Da
SUBCELLULAR LOCATION: Cytoplasm.
TISSUE SPECIFICITY: Expressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid C-cells. In the brain, the expression is restricted to distinct subtypes of neurons with highest expression in the molecular layer of the cerebellum (stellate and basket cells), in the anterior part of the pituitary gland, in the thalamus, in the hypothalamus and in a subgroup of neocortical neurons.
SIMILARITY: SwissProt: O76038 ## Contains 6 EF-hand domains.
MISCELLANEOUS: Detectable in human serum after ischemic neuronal damage.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at 4°C from date of shipment. 包装信息 数量 100 µg
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