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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Purified Polyclonal Antibody 描述 产品目录编号 ABS281 描述 Anti-eIF4B Antibody Alternate Names - eIF-4B
- Eukaryotic translation initiation factor 4B
背景信息 Eukaryotic translation initiation factor 4B (eIF4B) is an RNA-binding protein that is involved in translation of RNA molecules and consequent protein synthesis. It contains multiple domains, including an N-terminal RNA recognition motif (RRM) and a C-terminal Arginine Rich Motif (ARM) that facilitate RNA binding. eIF4B may play a specific role in the assembly of the 48S initiation complex. Its translational activity is enhanced by phosphorylation of its ser406 and ser422 residues via the Ras-MAPK and PI3-K/mTOR pathways. eIF4B specially targets RNA molecules involved in cell proliferation and survival in response to signals converging from these pathways. 产品信息 格式 Purified 控制 - HeLa cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect eIF4B using this Anti-eIF4B Antibody validated for use in Western Blotting, Immunoprecipitation. 主要应用 - Western Blotting
应用说明 Immunoprecipitation Analysis: 10 µg from a representative lot immunoprecipitated eIF4B from HeLa RIPA lysate 生物信息 免疫原品种 Recombinant protein corresponding to human eIF4B. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001408
基因符号 - EIF4B
纯化方法 Protein A purified UniProt编号 - P23588
产品使用声明 质量保证 Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected eIF4B in 10 µg of HeLa cell lysate.
使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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