• merck millipore,默克密理博,361547,GSK-3β Inhibitor VI - CAS 62673-69-2 - Calbiochem
  • merck millipore,默克密理博,361547,GSK-3β Inhibitor VI - CAS 62673-69-2 - Calbiochem

    产品名称:GSK-3β Inhibitor VI - CAS 62673-69-2 - Calbiochem
    产品型号:361547
    The GSK-3β Inhibitor VI, also referenced under CAS 62673-69-2, controls the biological activity of GSK-3β. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation appli More>>

    merck millipore,默克密理博,361547,GSK-3β Inhibitor VI - CAS 62673-69-2 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,361547,GSK-3β Inhibitor VI - CAS 62673-69-2 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₆H₃Br₂ClOS62673-69-2
    描述
    概述 A thienyl α-chloromethyl ketone compound that acts as a cell-permeable, irreversible, and non-ATP competitive inhibitor of GSK-3β (IC50 = 1 µM). This reactive alkylating agent is selective towards GSK-3β and does not affect PKA activity even at concentrations as high as 100 µM.
    产品目录编号 361547
    品牌系列 Calbiochem®
    同义词 2-Chloro-1-(4,5-dibromo-thiophen-2-yl)-ethanone
    参考
    参考 Conde, S., et al. 2003. J. Med. Chem. 46, 4631.
    产品信息
    CAS号 62673-69-2
    具有ATP竞争性 N
    形式 Orange solid
    Hill配方 C₆H₃Br₂ClOS
    化学配方 C₆H₃Br₂ClOS
    Molar Mass 318.4
    可逆 Y
    结构配方图像
    生物信息
    主靶 Gsk-3β
    主靶IC50 1 µM against Gsk-3β
    纯度 ≥90% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Shipped with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution in DMSO, aliquot and freeze (-20°). DMSO stock solutions are stable for up to 1 week at -20°C. For increased stability reconstitute in chloroform, aliquot, dry under a stream of inert gas, and freeze (-20°C). Reconstitute in fresh DMSO just prior to use.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,361547,GSK-3β Inhibitor VI - CAS 62673-69-2 - Calbiochem

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