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品种反应性 主要应用 宿主 格式 抗体类型 Sh, B, Gt, H, Po, R WB, IHC M Ascites Monoclonal Antibody 描述 产品目录编号 MAB5580 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Arrestin Antibody, visual Alternate Names - S-antigen, rod arrestin
- S-antigen
背景信息 Visual arrestin is a 48 kDa protein expressed exclusively in retinal photoreceptor cells where it regulates light-dependent signal transduction through G protein-coupled receptor (rhodopsin) activation. Visual arrestin is the major pathogenetic autoantigen in human autoimmume imflammatory eye disease. 产品信息 格式 Ascites 演示 Ascites fluid. Liquid. 应用 应用 Detect Arrestin using this Anti-Arrestin Antibody, visual validated for use in IH, IP & WB. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Western blot: 48kDa
Immunohistochemistry
Immunopurification of arrestin
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Porcine visual arrestin. 宿主 Mouse 特异性 Visual arrestin. The antibody has not been tested for reactivity to arrestin in other tissues. 同种型 IgG1 品种反应性 SheepBovineGoatHumanPigRat 抗体类型 Monoclonal Antibody 基因符号 - cArr
- ARR3
- Arrestin-C
- CAR
- ARRX
- C-arrestin
UniProt编号 - P79260
UniProt汇总 Function: Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase.
Tissue specificity: Retina and pineal gland. Also expressed in the anterior tissues such as the ciliary epithelium and iris epithelium.
Involvement in disease: S-antigen induces autoimmune uveitis.
Miscellaneous: Arrestin binds calcium By similarity.
Sequence similarities: Belongs to the arrestin family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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