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品种反应性 主要应用 宿主 格式 抗体类型 Ma WB M Ascites Monoclonal Antibody 描述 产品目录编号 MAB5566 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Tubulin α Antibody, detyrosinated 产品信息 格式 Ascites 演示 Liquid. Contains no preservative. 应用 应用 This Anti-Tubulin Antibody, α, detyrosinated is validated for use in WB for the detection of Tubulin. 主要应用 - Western Blotting
应用说明 (add note) 生物信息 免疫原品种 Synthetic peptide GEEEGE. 表位 detyrosinated 宿主 Mouse 特异性 Alpha tubulin, detyrosinated. 同种型 IgG2a 品种反应性 Mammals 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_006009.2
Entrez基因汇总 Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. 基因符号 - hum-a-tub1
- TUBA1A
- hum-a-tub2
- LIS3
- FLJ25113
- TUBA3
- B-ALPHA-1
UniProt编号 - Q71U36
UniProt汇总 FUNCTION: SwissProt: Q71U36 # Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
SIZE: 451 amino acids; 50136 Da
SUBUNIT: Dimer of alpha and beta chains.
PTM: Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively (By similarity).
SIMILARITY: SwissProt: Q71U36 ## Belongs to the tubulin family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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