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  • merck millipore,默克密理博,MAB5504,Anti-Vesicular Glutamate Transporter 2 Antibody

  • merck millipore,默克密理博,MAB5504,Anti-Vesicular Glutamate Transporter 2 Antibody

    产品名称：Anti-Vesicular Glutamate Transporter 2 Antibody
    产品型号：MAB5504
    Detect Vesicular Glutamate Transporter 2 using this Anti-Vesicular Glutamate Transporter 2 Antibody validated for use in WB, IH.

    merck millipore,默克密理博,MAB5504,Anti-Vesicular Glutamate Transporter 2 Antibody

  • 产品介绍
  • merck millipore,默克密理博,MAB5504,Anti-Vesicular Glutamate Transporter 2 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, H, MIHC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB5504
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Vesicular Glutamate Transporter 2 Antibody
    Alternate Names
    • VGLUT2
    背景信息 Vesicular Glutamate Transporter 2 (VGLUT2) is a sodium dependent inorganic phosphate cotransporter that is involved in the calcium dependent glutamate release from astrocytes. It is expressed in only a subset of neurons, localized to synaptic vesicles, at synapses exhibiting classical excitatory features. VGLUT2 mRNA is found in brain regions that lack VGLUT1, a related protein also displaying sodium dependent inorganic phosphate cotransporter activity.
    产品信息
    格式 Purified
    控制
    • Brain tissue
    演示 Mouse monoclonal in PBS containing 0.1% sodium azide.
    应用
    应用 Detect Vesicular Glutamate Transporter 2 using this Anti-Vesicular Glutamate Transporter 2 Antibody validated for use in WB, IH.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunohistochemistry: A 1:50-1:300 dilution of a previous lot worked using ABC with NiDAB on floating mouse brain sections.

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Recombinant protein from rat VGLUT2.
    克隆 8G9.2
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Reacts with VGLUT2 (Vesicular Glutamate Transporter 2).
    同种型 IgG1
    品种反应性 RatHumanMouse
    Species Reactivity Note Mouse and rat. Expected to react with human based on sequence homology.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_020346.1
    基因符号
    • VGLUT2
    • SLC17A6
    • DNPI
    纯化方法 Protein A purfied
    UniProt编号
    • Q9JI12
    UniProt汇总 FUNCTION: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas. May also mediate the transport of inorganic phosphate.
    SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane; Multi-pass membrane protein (Potential). Cell junction, synapse, synaptosome.
    TISSUE SPECIFICITY: Expressed in brain (at protein level). Expressed in brainstem, deep nuclei, septal nuclei, nuclei of the diagonal band, frontal cortex, hypothalamus, midbrain, parietal cortex and temporal cortex. Also expressed in pineal gland and islets of Langerhans.
    SIMILARITY: Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.

    SIZE: 582 amino acids; 64392 Da
    产品使用声明
    质量保证 Evaluated by Western Blot on Mouse brain lysates.

    Western Blotting Analysis: 1:500 dilution of this antibody detected VGLUT2 on 10 µg of Mouse brain lysates.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB5504,Anti-Vesicular Glutamate Transporter 2 Antibody

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