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merck millipore,默克密理博,MAB5270-100UG,Anti-Choline Acetyltransferase Antibody, clone 1.B3.9B3
产品名称:Anti-Choline Acetyltransferase Antibody, clone 1.B3.9B3
产品型号:MAB5270-100UG
This Anti-Choline Acetyltransferase Antibody, clone 1.B3.9B3 is validated for use in ELISA, IH, IH(P), WB for the detection of Choline Acetyltransferase.
merck millipore,默克密理博,MAB5270-100UG,Anti-Choline Acetyltransferase Antibody, clone 1.B3.9B3
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, Po WB, ELISA, IHC M Purified Monoclonal Antibody 描述 产品目录编号 MAB5270-100UG 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Choline Acetyltransferase Antibody, clone 1.B3.9B3 Alternate Names - ChAT
产品信息 格式 Purified 控制 - Brain tissue
演示 Purified immunoglobulin. Lyophilized from 0.02 M Phosphate buffer, 0.25 M NaCl with 0.1% sodium azide. Reconstitute to 100 μg/mL with sterile distilled water. 应用 应用 This Anti-Choline Acetyltransferase Antibody, clone 1.B3.9B3 is validated for use in ELISA, IH, IH(P), WB for the detection of Choline Acetyltransferase. 主要应用 - Western Blotting
- ELISA
- Immunohistochemistry
应用说明 Western blot
ELISA
Immunohistochemistry: 10-20 μg/mL in paraffin embedded sections {See Ratcliffe et al. 1998}
Optimal working dilutions and protocols must be determined by end user.生物信息 免疫原品种 Highly purified ChAT obtained from porcine brain (Ostermann-Fatif et al., 1990). 克隆 1.B3.9B3 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 Reacts with choline acetyltransferase (ChAT)-positive cells from humans, rats and pigs (Ostermann-Fatif et al., 1992a,b). 同种型 IgG1 品种反应性 RatHumanPig 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_020986.2
- NM_020549.3
- NM_020984.2
- NM_020985.2
Entrez基因汇总 Cholinergic systems are implicated in numerous neurologic functions. Alteration in some cholinergic neurons may account for the disturbances of Alzheimer disease. The protein encoded by this gene synthesizes the neurotransmitter acetylcholine. Alternative splice variants have been found that contain alternative 5' untranslated exons. Three of the four described splice variants encode identical 69 kDa proteins while one variant encodes both the 69 kDa and a larger 82 kDa protein. 基因符号 - EC 2.3.1.6
- CHAT
- ChAT
- CMS1A2
- CHOACTase
- CMS1A
纯化方法 Protein A purfied UniProt编号 - P28329
UniProt汇总 FUNCTION: SwissProt: P28329 # Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.
SIZE: 748 amino acids; 82568 Da
DISEASE: SwissProt: P28329 # Defects in CHAT are the cause of familial infantile myasthenia gravis 2 (FIMG2) [MIM:254210, 254200]; also known as CMS-EA. FIMG2 patients have myasthenic symptoms since birth or early infancy, negative tests for anti-AChR antibodies, and abrupt episodic crises with increased weakness, bulbar paralysis, and apnea precipitated by undue exertion, fever, or excitement. Inheritance is autosomal recessive.
SIMILARITY: SwissProt: P28329 ## Belongs to the carnitine/choline acetyltransferase family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain lyophilized antibody at 2–8°C in undiluted aliquots for up to 6 months. Maintain reconstituted antibody at -20°C in undiluted aliquots for up to 6 months. 包装信息 数量 100 µg
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