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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS764 Replaces MABS402 描述 Anti-GPAT-1 Antibody Alternate Names - GPAT-1
- Glycerol-3-phosphate acyltransferase 1, mitochondrial
背景信息 Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAT-1) is located on the mitochondrial outer membrane, allowing reciprocal regulation with carnitine palmitoyltransferase-1. It is thought to be critical for the development of hepatic steatosis; steatosis triggered by GPAT-1 overexpression leads to hepatic and possibly peripheral insulin resistance. GPAT-1 is transcriptionally upregulated by insulin and sterol regulatory element binding protein (SREBP-1) and downregulated by AMP-activated protein kinase. Mice deficient in GPAT-1 exhibit decreased triacylglycerol (TAG) in cardiomyocytes even in high-fat diets, suggesting that GPAT-1 contributes significantly to TAG accumulation in heart tissue during lipogenic or high fat diets. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-GPAT-1 Antibody is an antibody against GPAT-1 for use in western blotting, IHC & immunofluorescence. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 2.5 μg/mL from a representative lot detected GPAT-1 in rat brain tissue.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected GPAT-1 in rat brain cells.
生物信息 免疫原品种 KLH-conjugated synthetic peptide corresponding to the C-terminus of human GPAT-1. 表位 C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Rat 抗体类型 Polyclonal Antibody 基因符号 - GPAT1
- GPAM
纯化方法 Antigen Affinity purified UniProt编号 - Q9HCL2
产品使用声明 质量保证 Evaluated by Western Blotting in rat brain tissue lysate.
Western Blotting Analysis: 2 μg/mL of this antibody detected GPAT-1 in rat brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,3867,Hydrocortisone - CAS 50-23-7 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,17-10262,ChIPAb+™ JMJD1C - ChIP Validated Antibody and Primer Set
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