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品种反应性 主要应用 宿主 格式 抗体类型 R, M ICC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MAB5204 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Agrin Antibody 产品信息 格式 Purified 演示 Purified immunoglobulin. Liquid in PBS containing 50% glycerol and 0.09% sodium azide. 应用 应用 Anti-Agrin Antibody is an antibody against Agrin for use in WB & IC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunocytochemistry: 10 μg/mL
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Recombinant rat agrin (C-terminal construct) 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 MAB5204 recognizes rat and mouse agrin. The epitope has been mapped near the splicing site Z. Binding of this antibody to agrin causes marked reduction in nAChR clusters. 同种型 IgG1 品种反应性 RatMouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_198576.2
Entrez基因汇总 Agrin is a neuronal aggregating factor that induces the aggregation of acetylcholine receptors and other postsynaptic proteins on muscle fibers and is crucial for the formation of the neuromuscular junction.[supplied by OMIM] 基因符号 - AGRIN
- AGRN
- agrin
- OTTHUMP00000044043
- FLJ45064
UniProt编号 - O00468
UniProt汇总 FUNCTION: SwissProt: O00468 # Component of the basal lamina that causes the aggregation of acetylcholine receptors and acetylcholine-esterase on the surface of muscle fibers of the neuromuscular junction (By similarity).
SIZE: 2045 amino acids; 214846 Da
SUBUNIT: Binds to laminin.
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix. Note=Synaptic basal lamina at the neuromuscular junction (By similarity).
PTM: Contains heparan sulfate chains as well as N-linked and O- linked oligosaccharides (By similarity).
SIMILARITY: SwissProt: O00468 ## Contains 4 EGF-like domains. & Contains 9 Kazal-like domains. & Contains 2 laminin EGF-like domains. & Contains 3 laminin G-like domains. & Contains 1 NtA (N-terminal agrin) domain. & Contains 1 SEA domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain lyophilized at material -20°C or below for up to 12 months. After reconstitution maintain at -20°C to -70°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. 包装信息 数量 200 µg
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