merck millipore,默克密理愽
  • merck millipore,默克密理博,AB1597P,Anti-Vesicular Monoamine Transporter 1 Antibody

  • merck millipore,默克密理博,AB1597P,Anti-Vesicular Monoamine Transporter 1 Antibody

    产品名称：Anti-Vesicular Monoamine Transporter 1 Antibody
    产品型号：AB1597P
    Anti-Vesicular Monoamine Transporter 1 Antibody detects level of Vesicular Monoamine Transporter 1 & has been published & validated for use in ELISA, IH & WB.

    merck millipore,默克密理博,AB1597P,Anti-Vesicular Monoamine Transporter 1 Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB1597P,Anti-Vesicular Monoamine Transporter 1 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, MWB, ELISA, IHCRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB1597P
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Vesicular Monoamine Transporter 1 Antibody
    Alternate Names
    • VMAT1
    产品信息
    格式 Affinity Purified
    演示 Affinity purified immunoglobulin. Liquid in PBS with 0.1% BSA.
    应用
    应用 Anti-Vesicular Monoamine Transporter 1 Antibody detects level of Vesicular Monoamine Transporter 1 & has been published & validated for use in ELISA, IH & WB.
    主要应用
    • Western Blotting
    • ELISA
    • Immunohistochemistry
    应用说明 Western blot: 1-10 μg/mL (Chemiluminescence technique)

    Immunohistochemistry: 1-20 μg/mL on paraformaldehyde fixed sections.

    ELISA: 0.5-1.0 μg/mL (1 μg/mL VMAT1 peptide (Catalog Number AG250)/well)

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 A 12 amino acid C-terminal peptide sequence from rat VMAT1 (Liu et al. 1992). This peptide is predicted to be cytoplasmic.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Vesicular Monoamine Transporter 1 (VMAT1). An antibody made to the C-terminal VMAT1 peptide detected a major band at ~55 kDa in postnuclear supernatants of CHO transfected with VMAT1 and not in wild type cells (Liu et al. 1994). Some additional bands, both higher and lower molecular weight, were also detected and remain unaffected by the inclusion of protease inhibitors. VMAT1 has been localized in adrenal chromaffin cells, endocrine and paracrine cells associated with the intestine, stomach and sympathetic nervous system (Liu et al. 1994; Weihe et al. 1994). VMAT1 has also been found in endosomes of transfected CHO cells and in LDCVs of rat PC12 cells (Liu et al. 1994). This antibody is not expected to cross-react with human VMAT1 (Erickson et al. 1996).
    品种反应性 RatMouse
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_003053.1
    Entrez基因汇总 The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM]
    基因符号
    • VMAT1
    • SLC18A1
    • VAT1
    • CGAT
    UniProt编号
    • P54219
    UniProt汇总 FUNCTION: SwissProt: P54219 # Involved in the vesicular transport of biogenic amines.
    SIZE: 525 amino acids; 56257 Da
    SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane; Multi-pass membrane protein.
    SIMILARITY: SwissProt: P54219 ## Belongs to the major facilitator superfamily. Vesicular transporter family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µg

    merck millipore,默克密理博,AB1597P,Anti-Vesicular Monoamine Transporter 1 Antibody

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