merck millipore,默克密理博,MAB4423C3,Anti-SOX-2 Antibody, clone 10H9.1, Cy3 conjugate

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
M, H	ICC	M	Cy3	Monoclonal Antibody

描述
产品目录编号	MAB4423C3
描述	Anti-SOX-2 Antibody, clone 10H9.1, Cy3 conjugate
Alternate Names	SRY related HMG BOX gene 2 SOX2 ANOP3 MCOPS3 MGC2413
背景信息	SOX-2 is also known as SRY related HMG BOX gene 2. All SOX proteins have a single HMG box and bind linear DNA in a sequence-specific manner, resulting in the bending of DNA through large angles. Bending causes the DNA helix to open for some distance, which may affect binding and interactions of other transcription factors. SOX1, SOX2 and SOX3 show the closest homology to SRY. They share maximum homology within the HMG domain and are expressed mainly in the developing nervous system of the mouse. These genes share significant homology outside the HMG box also and are highly conserved throughout their evolution. Sox-2 plays a key role in embryonic stem cell development, and has been shown to help stem cells maintain a pluripotent potential. It has also been shown to be associated with uncommitted dividing stem cell and precursor cells of the developing CNS. SOX-2 has been identified as a key transcription factor required for cellular reprogramming.

产品信息
格式	Cy3
控制	Mouse Embryonic Stem Cells (SCR012).
演示	Purified mouse monoclonal IgG2b conjugated to Cy3 in PBS with 0.1% sodium azide and 15mg/ml BSA.

应用
应用	Anti-SOX-2 Antibody, clone 10H9.1, Cy3 conjugate is an antibody against SOX-2 for use in ICC.
主要应用	Immunocytochemistry
应用说明	Evaluated by Immunocytochemistry in H9 Human Embryonic Stem Cells. Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected SOX-2 in H9 Human Embryonic Stem Cells.

生物信息
免疫原品种	recombinant protein corresponding to human SOX-2.
宿主	Mouse
同种型	IgG2bκ
品种反应性	MouseHuman
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_003097
基因符号	SOX2
纯化方法	Protein G purified
UniProt编号	P48431

产品使用声明
质量保证	Evaluated by Immunocytochemistry in Mouse Embryonic Stem Cells (SCR012). Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected SOX-2 in Mouse Embryonic Stem Cells (SCR012).
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.

包装信息
数量	100 µL

merck millipore,默克密理博,MAB4423C3,Anti-SOX-2 Antibody, clone 10H9.1, Cy3 conjugate

whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech