merck millipore,默克密理博,MAB4401A4,Anti-Oct-4 Antibody, clone 10H11.2, Alexa Fluor 488 conjugate

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	ICC	M	AlexaFluor®488	Monoclonal Antibody

描述
产品目录编号	MAB4401A4
描述	Anti-Oct-4 Antibody, clone 10H11.2, Alexa Fluor® 488 conjugate
Alternate Names	octamer-binding transcription factor-3 OCT3/4 Octamer-binding transcription factor 3 POU class 5 homeobox 1 POU domain, class 5, transcription factor 1 POU-type homeodomain-containing DNA-binding protein
背景信息	Octamer-4 (Oct-4), a member of the POU family of transcription factors, has been demonstrated to be vital for the formation of self-renewing pluripotent stem cells. During embryogenesis expression of Oct-4 is limited to pluripotent cells of the inner cell mass (ICM) that contribute to the formation of all fetal cell types. This relationship between Oct-4 and pluripotency has seen this transcription factor emerge as a marker of pluripotent stem cells. Undifferentiated human and murine pluripotent Embryonic Stem (ES) and Embryonic Carcinoma (EC) cells express Oct-4. Additionally, murine Embryonic Germ (EG) cells are also known to express Oct-4. Following stem cell differentiation, the level of Oct-4 expression decreases. Oct-4 has been indentified as one of the key genes used to reprogram somatic cells into induced pluripotent stem cells (iPS cells).

产品信息
格式	AlexaFluor®488
控制	H9 human embryonic stem cells.
演示	Purified mouse monoclonal IgG1 conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15mg/ml BSA.

应用
应用	This Anti-Oct-4 Antibody, clone 10H11.2, Alexa Fluor 488 conjugate is validated for use in ICC for the detection of 41186.
主要应用	Immunocytochemistry
应用说明	Evaluated by Immunocytochemistry in mouse embryonic stem cells (SCR012). Immunocytochemsitry Analysis: A 1:100 dilution of this antibody did not detect Oct-4 in mouse embryonic stem cells (SCR012).

生物信息
免疫原品种	Recombinant GST fusion protein, human Oct-4 (aa 1-134).
克隆	clone 10H11.2
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	This antibody recognizes human Oct-4. Antibody is not reactive with mouse Oct-4 protein.
同种型	IgG1
品种反应性	Human
Species Reactivity Note	Demonstrated to react with Human. Antibody is not reactive with mouse Oct-4 protein.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_002692
基因符号	Oct-4 POU5F1 Oct-3 MGC22487 Oct4 OTF4 OTF3 OCT3 OCT4
纯化方法	Protein A purified
UniProt编号	Q01860

产品使用声明
质量保证	Evaluated by Immunocytochemistry in H9 human embryonic stem cells. Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected Oct-4 in H9 human embryonic stem cells.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.

包装信息
数量	100 µL

merck millipore,默克密理博,MAB4401A4,Anti-Oct-4 Antibody, clone 10H11.2, Alexa Fluor 488 conjugate

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