merck millipore,默克密理博,MAB4372,Anti-ID-1 Antibody, clone 7D4.2

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
M, H	WB	M	Purified	Monoclonal Antibody

描述
产品目录编号	MAB4372
品牌系列	Chemicon®
商名	Chemicon
描述	Anti-ID-1 Antibody, clone 7D4.2
背景信息	Id-1 is an inhibitor of differentiation protein, which, along with Id2, Id3 and Id4, plays a key role in the regulation of lineage commitment, cell fate decisions and in the timing of differentiation during neurogenesis, lymphopoiesis and neovascularisation (angiogenesis). Id proteins, induced by the bone morphogenic protein-SMAD pathway, have also been shown to collaborate with LIF to ensure that embryonic stem cells opt for self-renewal.

产品信息
格式	Purified
演示	Supplied in PBS Buffer, pH 7.0 with 0.1% sodium azide

应用
应用	Detect ID-1 using this Anti-ID-1 Antibody, clone 7D4.2 validated for use in Mplex, IF & WB.
主要应用	Western Blotting

生物信息
免疫原品种	Recombinant ID-1 protein
克隆	7D4.2
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
同种型	IgG1
品种反应性	MouseHuman
抗体类型	Monoclonal Antibody
Entrez基因编号	NM_181353.1 NM_002165.2
Entrez基因汇总	The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
基因符号	ID ID1
UniProt编号	P41134
UniProt汇总	FUNCTION: SwissProt: P41134 # ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. SIZE: 155 amino acids; 16133 Da SUBUNIT: Heterodimer with other HLH proteins. Interacts with COPS5 (By similarity). SUBCELLULAR LOCATION: Nucleus. DEVELOPMENTAL STAGE: Expression correlates with proliferation in some types of cells. SIMILARITY: SwissProt: P41134 ## Contains 1 basic helix-loop-helix (bHLH) domain.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.

包装信息
数量	100 µg

merck millipore,默克密理博,MAB4372,Anti-ID-1 Antibody, clone 7D4.2

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