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merck millipore,默克密理博,MAB4122,Anti-Multi-Drug Resistance Related Protein Antibody, clone MRPm6
产品名称：Anti-Multi-Drug Resistance Related Protein Antibody, clone MRPm6
产品型号：MAB4122
Anti-Multi-Drug Resistance Related Protein Antibody, clone MRPm6 is an antibody against Multi-Drug Resistance Related Protein for use in FC, WB, IH(P).
merck millipore,默克密理博,MAB4122,Anti-Multi-Drug Resistance Related Protein Antibody, clone MRPm6
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB, FC M Culture Supernatant Monoclonal Antibody 描述 产品目录编号 MAB4122 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Multi-Drug Resistance Related Protein Antibody, clone MRPm6 Alternate Names - MRP
产品信息 格式 Culture Supernatant 演示 Tissue Culture Supernatant. Liquid containing 0.1% sodium azide and 0.7% BSA. 应用 应用 Anti-Multi-Drug Resistance Related Protein Antibody, clone MRPm6 is an antibody against Multi-Drug Resistance Related Protein for use in FC, WB, IH(P). 主要应用 - Western Blotting
- Flow Cytometry
应用说明 Western blot
Flow Cytometry
Immunohistochemistry on frozen and paraffin embedded tissue
sections: 1:20.
Note: For cellular detection permeabilization is required.
Optimal working dilutions must be determined by end user.生物信息 克隆 MRPm6 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 MRPm6 reacts with an internal epitope of MRP, a 180-195 kDa transmembrane transporter protein overexpressed in various human non-P-glycoprotein MDR tumor cell lines. MRPm6 was raised against a bacterial fusion protein of MRP, containing a segment of 170 amino acids in the carboxy terminal end and part of the carboxy proximal nucleotide binding domain of the protein. MRPm6 does not cross-react with the human MDR1 and MDR3 gene products (Flens et al., 1994). 同种型 IgG1 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_019900.2
- NM_019901.1
- NM_019902.1
- NM_004996.3
- NM_019862.2
- NM_019898.2
- NM_019899.2
Entrez基因汇总 The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms. 基因符号 - DKFZp686N04233
- ABCC1
- 4transporter)
- ABC29
- GS-X
- ABCC
- MRP1
- DKFZp781G125
- MRP
UniProt编号 - P33527
UniProt汇总 FUNCTION: SwissProt: P33527 # May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Confers resistance to anticancer drugs. Transports LTC4. May protect milk against xenobiotics (By similarity).
SIZE: 1531 amino acids; 171561 Da
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Lung, testis and peripheral blood mononuclear cells.
SIMILARITY: SwissProt: P33527 ## Belongs to the ABC transporter family. Conjugate transporter (TC 3.A.1.208) subfamily. & Contains 2 ABC transmembrane type-1 domains. & Contains 2 ABC transporter domains.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at -20°C in undiluted aliquots. May be stored at 2-8°C for short term use. Avoid repeated freeze-thaw cycles. 包装信息 数量 100 µg
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