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品种反应性 主要应用 宿主 格式 抗体类型 H WB M Ascites Monoclonal Antibody 描述 产品目录编号 MAB3698 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Rad51D Antibody, clone 5B3 产品信息 格式 Ascites 演示 Ascites fluid. Liquid. Contains no preservative. 应用 应用 Detect Rad51D with Anti-Rad51D Antibody, clone 5B3 (Mouse Monoclonal Antibody), that has been shown to work in WB. 主要应用 - Western Blotting
应用说明 Western blot
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Recombinant human Rad51D 克隆 5B3 宿主 Mouse 特异性 Rad51D. No cross reactivity with Rad51B, Rad51C, XRCC2 or XRCC3 by Western blot. 同种型 IgG1 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_133629.1
- NM_002878.2
Entrez基因汇总 The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, which are known to be involved in the homologous recombination and repair of DNA. This protein forms a complex with several other members of the RAD51 family, including RAD51L1, RAD51L2, and XRCC2. The protein complex formed with this protein has been shown to catalyze homologous pairing between single- and double-stranded DNA, and is thought to play a role in the early stage of recombinational repair of DNA. Several alternatively spliced transcript variants of this gene have been described, but the biological validity of some of them has not been determined. 基因符号 - RAD51D
- RAD51L3
- R51H3
- Trad
- TRAD
- HsTRAD
UniProt编号 - O75771
UniProt汇总 FUNCTION: SwissProt: O75771 # Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
SIZE: 328 amino acids; 35049 Da
SUBUNIT: Part of a BCDX2 complex consisting of RAD51B, RAD51C, RAD51D and XRCC2. Part of a complex consisting of RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3. Interacts with ZSWIM7.
SUBCELLULAR LOCATION: Nucleus (Probable).
TISSUE SPECIFICITY: Expressed in colon, prostate, spleen, testis, ovary, thymus and small intestine. Weakly expressed in leukocytes.
SIMILARITY: SwissProt: O75771 ## Belongs to the recA family. RAD51 subfamily.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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