merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB5260-60UG,Anti-Nerve Growth Factor Antibody, clone 27/21

  • merck millipore,默克密理博,MAB5260-60UG,Anti-Nerve Growth Factor Antibody, clone 27/21

    产品名称：Anti-Nerve Growth Factor Antibody, clone 27/21
    产品型号：MAB5260-60UG
    This Anti-Nerve Growth Factor Antibody, clone 27/21 is validated for use in ELISA for the detection of Nerve Growth Factor.

    merck millipore,默克密理博,MAB5260-60UG,Anti-Nerve Growth Factor Antibody, clone 27/21

  • 产品介绍
  • merck millipore,默克密理博,MAB5260-60UG,Anti-Nerve Growth Factor Antibody, clone 27/21

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, B, H, MELISAMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB5260-60UG
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Nerve Growth Factor Antibody, clone 27/21
    Alternate Names
    • NGF
    产品信息
    格式 Purified
    演示 Purified immunoglobulin. Lyophilized from 0.02M Phosphate buffer, 0.25M NaCl with 0.1% sodium azide. Reconstitute with 1 mL of sterile distilled water.
    应用
    应用 This Anti-Nerve Growth Factor Antibody, clone 27/21 is validated for use in ELISA for the detection of Nerve Growth Factor.
    主要应用
    • ELISA
    应用说明 ELISA

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 2.5 S form of mouse NGF.
    克隆 27/21
    宿主 Mouse
    特异性 NGF is a neurotrophic protein which is synthesized by the target tissues of NGF-sensitive neurons. NGF acts on sympathetic and sensoric neurons as well as on cholinergic neurons of the basal forebrain. It has been suggested that NGF is involved in the neuropathology of Alzheimer's Disease (Hefti & Weiner, 1986). In the peripheral nervous system, NGF plays a role in the development of autonomic and sensory neuropathies (Anand et al., 1991).

    The antibody specifically reacts with the beta -subunit of NGF from mouse, in the 2.5S- as well as in the 7S-form.

    The cross-reactivity with human NGF is 60-90 % of the reactivity with mouse NGF
    同种型 IgG1
    品种反应性 RatBovineHumanMouse
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_002527.4
    • NM_001102654.1
    Entrez基因汇总 The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
    基因符号
    • NT-3
    • NTF3
    • NT3
    • NGF2
    • HDNF
    • MGC129711
    • NGF-2
    UniProt编号
    • P20783
    UniProt汇总 FUNCTION: SwissProt: P20783 # Seems to promotes the survival of visceral and proprioceptive sensory neurons.
    SIZE: 257 amino acids; 29355 Da
    SUBCELLULAR LOCATION: Secreted.
    TISSUE SPECIFICITY: Brain and peripheral tissues.
    SIMILARITY: SwissProt: P20783 ## Belongs to the NGF-beta family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 The lyophilized antibody is stable if stored dry at 2-8°C for up to 12 months. After reconstitution maintain at 4°C unaliquotted but sealed tightly for 6 months; do not freeze thaw.
    包装信息
    数量 60 µg

    merck millipore,默克密理博,MAB5260-60UG,Anti-Nerve Growth Factor Antibody, clone 27/21

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