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merck millipore,默克密理博,MAB3684,Anti-Cyclin B1 Antibody, clone V152
产品名称：Anti-Cyclin B1 Antibody, clone V152
产品型号：MAB3684
Detect Cyclin B1 with Anti-Cyclin B1 Antibody, clone V152 (Mouse Monoclonal Antibody), that has been shown to work in WB, IHC(P).
merck millipore,默克密理博,MAB3684,Anti-Cyclin B1 Antibody, clone V152
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H WB M Ascites Monoclonal Antibody 描述 产品目录编号 MAB3684 Replaces 04-220 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Cyclin B1 Antibody, clone V152 产品信息 格式 Ascites 演示 Ascites fluid. Liquid. Contains no preservative. 应用 应用 Detect Cyclin B1 with Anti-Cyclin B1 Antibody, clone V152 (Mouse Monoclonal Antibody), that has been shown to work in WB, IHC(P). 主要应用 - Western Blotting
应用说明 Western blot
Immunohistochemistry (works on paraffin embedded tissue sections)
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Hamster Cyclin B1. 克隆 V152 宿主 Mouse 特异性 Cyclin B. Cyclin B1 is a marker of cell proliferation and a key component of the cell progression machinery. MAB3684 works well for detecting Cyclin B1 by Western blot and immunohistochemistry. 同种型 IgG1 品种反应性 MouseHuman 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_031966.2
Entrez基因汇总 The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. 基因符号 - CCNB
- CCNB1
UniProt编号 - P14635
UniProt汇总 FUNCTION: SwissProt: P14635 # Essential for the control of the cell cycle at the G2/M (mitosis) transition.
SIZE: 433 amino acids; 48337 Da
SUBUNIT: Interacts with the CDC2 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex. Binds HEI10. Interacts with catalytically active RALBP1 and CDC2 during mitosis to form an endocytotic complex during interphase.
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Centrosome.
DEVELOPMENTAL STAGE: Accumulates steadily during G2 and is abruptly destroyed at mitosis.
PTM: Ubiquitinated by the SCF(NIPA) complex during interphase, leading to its destruction. Not ubiquitinated during G2/M phases.
SIMILARITY: SwissProt: P14635 ## Belongs to the cyclin family. Cyclin AB subfamily.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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