merck millipore,默克密理愽
  • merck millipore,默克密理博,344152,FPT Inhibitor II - Calbiochem

  • merck millipore,默克密理博,344152,FPT Inhibitor II - Calbiochem

    产品名称：FPT Inhibitor II - Calbiochem
    产品型号：344152
    The FPT Inhibitor II controls the biological activity of FPT. This small molecule/inhibitor is primarily used for Cancer applications.

    merck millipore,默克密理博,344152,FPT Inhibitor II - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,344152,FPT Inhibitor II - Calbiochem

    重要规格表

    经验配方
    C₁₇H₂₈NO₅P • 2Na • 3H₂O
    描述
    概述 A cell permeable potent and selective inhibitor of farnesyltransferase (FTase; IC50 = 75 nM). Also inhibits Ras farnesylation in whole cells by ~90% at 25-250 µM. Resistant to cleavage by phosphorylation.
    产品目录编号 344152
    品牌系列 Calbiochem®
    同义词 (E,E)-2-[2-Oxo-2-[[(3,7,11-trimethyl-2,6,10-dodecatrienyl)oxy]amino]ethyl]phosphonic Acid, 2Na
    参考
    参考 Manne, V., et al. 1995. Drug Development Res. 34, 121.
    产品信息
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₁₇H₂₈NO₅P • 2Na • 3H₂O
    化学配方 C₁₇H₂₈NO₅P • 2Na • 3H₂O
    Molar Mass 457.4
    吸湿 Hygroscopic
    可逆 N
    结构配方图像
    生物信息
    主靶 Farnesyltransferase (Ftase)
    主靶IC50 75 nM against Ftase
    纯度 ≥95% by TLC
    理化信息
    细胞可渗透 Y
    溶解度 H₂O
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.

    merck millipore,默克密理博,344152,FPT Inhibitor II - Calbiochem

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