merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB364,Anti-MAP2A, 2B, 2C Antibody, clone HM-2

  • merck millipore,默克密理博,MAB364,Anti-MAP2A, 2B, 2C Antibody, clone HM-2

    产品名称：Anti-MAP2A, 2B, 2C Antibody, clone HM-2
    产品型号：MAB364
    Anti-MAP2A Antibody, 2B, 2C, clone HM-2 detects level of MAP2A & has been published & validated for use in WB, IH.

    merck millipore,默克密理博,MAB364,Anti-MAP2A, 2B, 2C Antibody, clone HM-2

  • 产品介绍
  • merck millipore,默克密理博,MAB364,Anti-MAP2A, 2B, 2C Antibody, clone HM-2

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Qu, B, Ch, H, M, RIHC, WBMAscitesMonoclonal Antibody
    描述
    产品目录编号 MAB364
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-MAP2A, 2B, 2C Antibody, clone HM-2
    产品信息
    格式 Ascites
    演示 Ascites fluid. Liquid with 15 mM sodium azide.
    应用
    应用 Anti-MAP2A Antibody, 2B, 2C, clone HM-2 detects level of MAP2A & has been published & validated for use in WB, IH.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunoblotting at 1:500 using fresh rat brain extract or enriched microtubule protein preparation.

    Immunohistochemistry: 1:50 to 1:1000

    Optimal working dilution must be determined by the end user.
    生物信息
    免疫原品种 Rat brain microtubule-associated protein.
    克隆 HM-2
    宿主 Mouse
    特异性 Shows selective staining of dendritic trees throughout the brain in immunohistochemical staining of brain tissue. In perkinje neurons, staining is restricted to the dendrites distal to the initial dendrite segment. No staining of cell body in mature Perkinje cells but strong staining of cell bodies of developing Perkinje cells from neonatal rats. No detectable staining of axons or non-neuronal cells. Reacts specifically with all forms of MAP2 (MAP2a ~280 kDa, MAP2b ~280 kDa and MAP2c ~70 kDa) as determined by immunoblot. No cross-reactivity observed to other MAPs or tubulin.
    同种型 IgG1
    品种反应性 QuailBovineChickenHumanMouseRat
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_031847.2
    • NM_001039538.1
    • NM_002374.3
    • NM_031845.2
    Entrez基因汇总 This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isforms have been described.
    基因符号
    • MAP2A
    • MAP2
    • MAP2B
    • MAP-2
    • MAP2C
    • DKFZp686I2148
    UniProt编号
    • P11137
    UniProt汇总 FUNCTION: SwissProt: P11137 # The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
    SIZE: 1827 amino acids; 199539 Da
    PTM: MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.
    SIMILARITY: SwissProt: P11137 ## Contains 3 Tau/MAP repeats.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MAB364,Anti-MAP2A, 2B, 2C Antibody, clone HM-2

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