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merck millipore,默克密理博,MAB3402X,Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5, Alexa Fluor 488
产品名称：Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5, Alexa Fluor 488
产品型号：MAB3402X
Detect Glial Fibrillary Acidic Protein using this Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5, Alexa Fluor 488 validated for use in IC, IH.
merck millipore,默克密理博,MAB3402X,Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5, Alexa Fluor 488
- 产品介绍
- merck millipore,默克密理博,MAB3402X,Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5, Alexa Fluor 488
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, Ch, H, Po IHC, ICC M AlexaFluor®488 Monoclonal Antibody 描述 产品目录编号 MAB3402X 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5, Alexa Fluor® 488 Alternate Names - GFAP
产品信息 格式 AlexaFluor®488 演示 Purified immunoglobulin conjugated to Alexa Fluor® 488. Liquid in Phosphate buffer with 15 mg/mL BSA as a stabilizer and 0.1% sodium azide. 应用 应用 Detect Glial Fibrillary Acidic Protein using this Anti-Glial Fibrillary Acidic Protein Antibody, clone GA5, Alexa Fluor 488 validated for use in IC, IH. 主要应用 - Immunohistochemistry
- Immunocytochemistry
应用说明 Immunocytochemistry
Immunohistochemistry
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Purified glial filament (1). 克隆 clone GA5 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 The antibody reacts with GFAP from human, pig, chicken and rat. In tissue sections this antibody stains astrocytes and Bergman glia cells (1). 同种型 IgG1 品种反应性 RatChickenHumanPig 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_002055.2
Entrez基因汇总 This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant has been described, but its full length sequence has not been determined. 基因符号 - FLJ45472
- GFAP
UniProt编号 - P14136
UniProt汇总 FUNCTION: SwissProt: P14136 # GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
SIZE: 432 amino acids; 49880 Da
SUBUNIT: Isoform 3 interacts with N-terminus of PSEN1.
SUBCELLULAR LOCATION: Cytoplasm. Note=Associated with intermediate filaments.
DISEASE: SwissProt: P14136 # Defects in GFAP are a cause of Alexander disease [MIM:203450]. Alexander disease is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes. The most common form affects infants and young children, and is characterized by progressive failure of central myelination, usually leading to death usually within the first decade. Infants with Alexander disease develop a leukoencephalopathy with macrocephaly, seizures, and psychomotor retardation. Patients with juvenile or adult forms typically experience ataxia, bulbar signs and spasticity, and a more slowly progressive course.
SIMILARITY: SwissProt: P14136 ## Belongs to the intermediate filament family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
- Alexa Fluor® is a registered trademark of Molecular Probes, Inc.
储存和货运信息 存储条件 Maintain at 2-8°C in the dark for up to 6 months after date of receipt. 包装信息 数量 100 µg
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