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描述 概述 A fluorogenic substrate for caspase-9 (ICE-LAP6, Mch6). May also act as a substrate for caspase-4 and caspase-5. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore. 产品目录编号 218765 品牌系列 Calbiochem®
同义词 Ac-LEHD-AFC 参考 参考 Ito, A., et al. 1999. Biochim. Biophys. Acta 1452, 263.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.产品信息 具有ATP竞争性 N 形式 White solid 配方 Supplied as a trifluoroacetate salt. Hill配方 C₃₃H₃₈F₃N₇O₁₁ 化学配方 C₃₃H₃₈F₃N₇O₁₁ Molar Mass 765.7 肽序列 Ac-Leu-Glu-His-Asp-AFC 可逆 N 生物信息 主靶 A fluorogenic substrate for caspase-9 纯度 ≥95% by HPLC 理化信息 细胞可渗透 N 最大排放 ~505 nm 最大激励 ~400 nm 溶解度 DMSO 肽序列 Ac-Leu-Glu-His-Asp-AFC 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
防潮 Protect from moisture
无需冷冻 No
特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
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