merck millipore,默克密理博,SF-1149,BACE1; Human, Cyanine 5 RNA Detection Probe,SmartFlare

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Merck Millipore 默克密理愽

Entrez Gene Number	Species Reactivity	Species Reactivity Note
NM_001207048.1	H	NM_012104.4, NM_138972.3, NM_138971.3, NM_138973.3, NM_001207049.1

描述
产品目录编号	SF-1149
商名	SmartFlare
描述	BACE1; Human, Cyanine 5 RNA Detection Probe \| SmartFlare
Alternate Names	HSPC104 ASP2 BACE
背景信息	With SmartFlare™ RNA Detection probes, you can detect RNA in LIVE CELLS with ease. With just an overnight incubation of BACE1; Human, Cyanine 5 RNA Detection Probe you can detect the presence of BACE1 within your cells. BACE (β-secretase, β-site APP-cleaving enzyme) is a 70 kDa membrane associated aspartyl protease that is involved in the two step cleavage of amyloid β-peptide in the development of Alzheimer's disease. Once synthesized as a proteolytically inactive precursor form, the BACE protein undergoes post-translational modification in the ER, losing the pro-peptide and becomes glycosylated. The modified, mature protein is transported to the Golgi and then continues its migration to the membrane. Once in the membrane, BACE functions as the major source of β-secretase activity. BACE2, a homolog of BACE, has also been identified. BACE2 differs from BACE in that it is highly expressed in multiple tissues including colon, pancreas, and prostate rather than being restricted to the brain.

产品信息
格式	Cyanine 5
演示	Lyophilized

应用
应用	Use SmartFlare RNA Detection probes to measure gene expression in live cells. With an overnight incubation of SmartFlare BACE1, Human, Cyanine 5, you can detect BACE1 RNA levels within your cells.
主要应用	RNA Detection

产品使用声明
质量保证	SmartFlare Probes have been tested in a buffer system to detect the release of the fluorophore in the presence of a complimentary base pair sequence for each lot to confirm target specificity. SmartFlare Probes have also been tested in a cell model system and demonstrated increased fluorescence in cells expressing the target compared to a negative SmartFlare Scramble Control.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Store at 2–8°C in lyophilized format ONLY. Room temperature is required for reconstituted product.

包装信息
数量	250 reactions

merck millipore,默克密理博,SF-1149,BACE1; Human, Cyanine 5 RNA Detection Probe,SmartFlare

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