merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB3310,Anti-TIMP-2 Antibody, clone 67-4H11

  • merck millipore,默克密理博,MAB3310,Anti-TIMP-2 Antibody, clone 67-4H11

    产品名称：Anti-TIMP-2 Antibody, clone 67-4H11
    产品型号：MAB3310
    Anti-TIMP-2 Antibody, clone 67-4H11 detects level of TIMP-2 & has been published & validated for use in ELISA, WB, IH(P).

    merck millipore,默克密理博,MAB3310,Anti-TIMP-2 Antibody, clone 67-4H11

  • 产品介绍
  • merck millipore,默克密理博,MAB3310,Anti-TIMP-2 Antibody, clone 67-4H11

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Rb, B, Gp, Gt, H, M, RWB, ELISAMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB3310
    Replaces MAB3356
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-TIMP-2 Antibody, clone 67-4H11
    Alternate Names
    • Tissue Inhibitor of Metalloproteinase-2
    产品信息
    格式 Purified
    演示 Liquid in 0.1M Na-Phosphate buffer, pH 7.0 containing 2% protease free bovine serum albumin.
    应用
    应用 Anti-TIMP-2 Antibody, clone 67-4H11 detects level of TIMP-2 & has been published & validated for use in ELISA, WB, IH(P).
    主要应用
    • Western Blotting
    • ELISA
    应用说明 Immunoblotting

    Immunohistochemistry on paraffin-embedded, PLP fixed tissue at 5 μg/mL (see Tomita reference) or frozen tissues at 1 μg/mL (see Ohashi reference).

    ElA
    生物信息
    免疫原品种 Synthetic peptide corresponding to amino acids 178-193 of human TIMP-2 (numbered from the propeptide)

    YRGAAPPKQEFLDIED
    克隆 67-4H11
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 The antibody specifically reacts with human TIMP-2.

    SPECIES REACTIVITY:

    Cross-reacts with mouse, rat, guinea pig, rabbit and bovine TIMP-2.
    同种型 IgG1κ
    品种反应性 RabbitBovineGuinea PigGoatHumanMouseRat
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_003255.4
    Entrez基因汇总 This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
    基因符号
    • CSC-21K
    • TIMP2
    • TIMP-2
    UniProt编号
    • P16035
    UniProt汇总 FUNCTION: SwissProt: P16035 # Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
    SIZE: 220 amino acids; 24399 Da
    SUBCELLULAR LOCATION: Secreted.
    PTM: The activity of TIMP2 is dependent on the presence of disulfide bonds.
    SIMILARITY: SwissProt: P16035 ## Belongs to the protease inhibitor I35 (TIMP) family. & Contains 1 NTR domain.
    产品使用声明
    销售限制 This product is not available for sale in Japan.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    • Manufactured by Daiichi Fine Chemical Co., Ltd
    储存和货运信息
    存储条件 Maintain frozen at -20°C in undiluted aliquots for up to 12 months.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB3310,Anti-TIMP-2 Antibody, clone 67-4H11

上一件merck millipore产品：merck millipore,默克密理博,04-1035,Anti-SMAD3 Antibody, clone EP568Y, rabbit monoclonal
下一件merck millipore产品：merck millipore,默克密理博,MSBVN1250,MultiScreenHTS BV，1.2 µm，无色，非无菌


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