merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB2609,Anti-beta Arrestin 1 Antibody, clone 3H11.2

  • merck millipore,默克密理博,MAB2609,Anti-beta Arrestin 1 Antibody, clone 3H11.2

    产品名称：Anti-beta Arrestin 1 Antibody, clone 3H11.2
    产品型号：MAB2609
    Anti-beta Arrestin 1 Antibody, clone 3H11.2 detects level of beta Arrestin 1 & has been published & validated for use in WB & IF.

    merck millipore,默克密理博,MAB2609,Anti-beta Arrestin 1 Antibody, clone 3H11.2

  • 产品介绍
  • merck millipore,默克密理博,MAB2609,Anti-beta Arrestin 1 Antibody, clone 3H11.2

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB2609
    描述 Anti-beta Arrestin 1 Antibody, clone 3H11.2
    Alternate Names
    • retinal S-antigen (48 KDa protein)
    • Retinal S-antigen
    • Rod photoreceptor arrestin
    • S-antigen
    • retina and pineal gland (arrestin)
    • arrestin 1
    背景信息 The Arrestin family consists of four members: Arrestin 1 (visual Arrestin), Arrestin 2 (beta Arrestin 1), Arrestin 3 (beta Arrestin 2), and Arrestin 4 (cone Arrestin). While visual and cone Arrestins are found almost exclusively in the retina, beta Arrestins 1 and 2 are ubiquitously expressed. Beta Arrestins appear to act as negative regulators on G protein-coupled receptors, (Lefkowitz, 1998). Interaction with molecules such as clathrin, AP-2 and NSF directs the clathrin-mediated internalization of G-protein-coupled receptors. Interaction with molecules such as Src, Raf, Erk, ASK1 and JNK3 appears to regulate several pathways that result in the activation of MAP kinases, (Lin, 1998; Miller, 2001).
    产品信息
    格式 Purified
    控制
    • HEK293 cell lysate
    演示 Purified in PBS with 0.05% NaN3.
    应用
    应用 Anti-beta Arrestin 1 Antibody, clone 3H11.2 detects level of beta Arrestin 1 & has been published & validated for use in WB & IF.
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 KLH conjugated synthetic peptide corresponding to amino acids 357-372 of human beta arrestin 1.
    表位 a.a. 357-372
    克隆 clone 3H11.2
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Reacts with human beta-arrestin 1.
    同种型 IgMκ
    品种反应性 Human
    Species Reactivity Note Reacts with human. Other species have not been tested.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_004032.2
    Entrez基因汇总 Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known. [provided by RefSeq]
    基因符号
    • S-arrestin
    • ARRESTIN
    • S-AG
    纯化方法 Ammonium sulfate precipitation
    UniProt编号
    • P49407
    UniProt汇总 FUNCTION: Regulates beta-adrenergic receptor function. Beta-arrestins seem to bind phosphorylated beta-adrenergic receptors, thereby causing a significant impairment of their capacity to activate G(S) proteins.
    SEQUENCE SIMILARITIES: Belongs to the arrestin family.
    产品使用声明
    质量保证 Evaluated on a representative lot by Western blot in HEK293 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB2609,Anti-beta Arrestin 1 Antibody, clone 3H11.2

上一件merck millipore产品：merck millipore,默克密理博,ABS85,Anti-CPT2 Antibody
下一件merck millipore产品：merck millipore,默克密理博,MABN527,Anti-iNOS/NOS II, clone 13F5.1 Antibody


相关产品

merck millipore,默克密理博,AB9892,Anti-CRMP-2 Antibody merck millipore,默克密理博,AB9892,Anti-CRMP-2 Antibody

merck millipore,默克密理博,20-145,Assay Dilution Buffer, 5X merck millipore,默克密理博,20-145,Assay Dilution Buffer, 5X

merck millipore,默克密理博,441251,α₂-Macroglobulin, Human Plasma - Calbiochem merck millipore,默克密理博,441251,α₂-Macroglobulin, Human Plasma - Calbiochem

merck millipore,默克密理博,06-820,Anti-phospho-Adducin (Ser662) Antibody merck millipore,默克密理博,06-820,Anti-phospho-Adducin (Ser662) Antibody

merck millipore,默克密理博,ABS85,Anti-CPT2 Antibody merck millipore,默克密理博,ABS85,Anti-CPT2 Antibody

merck millipore,默克密理博,MABN527,Anti-iNOS/NOS II, clone 13F5.1 Antibody merck millipore,默克密理博,MABN527,Anti-iNOS/NOS II, clone 13F5.1 Antibody

merck millipore,默克密理博,612161,Anti-Tissue Factor Mouse mAb (TF9-10H10) merck millipore,默克密理博,612161,Anti-Tissue Factor Mouse mAb (TF9-10H10)

merck millipore,默克密理博,69047,S-protein HRP Conjugate merck millipore,默克密理博,69047,S-protein HRP Conjugate

merck millipore,默克密理博,524625,Phosphatase Inhibitor Cocktail Set II merck millipore,默克密理博,524625,Phosphatase Inhibitor Cocktail Set II

merck millipore,默克密理博,ABN478,Anti-LFG Antibody merck millipore,默克密理博,ABN478,Anti-LFG Antibody


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部