merck millipore,默克密理博,MAB2146,Anti-ICAM-1 Antibody, clone P2A4

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	IHC, ELISA, FC, ICC	M	Purified	Monoclonal Antibody

产品信息
格式	Purified
演示	Nonsterile liquid contains 0.2M phosphate buffer, 0.25M sodium chloride, and 0.1% sodium azide. Filtered through a 0.45 micron membrane filter.

应用
应用	Anti-ICAM-1 Antibody, clone P2A4 is an antibody against ICAM-1 for use in ELISA, FC, IP, IC, IH.
主要应用	Immunohistochemistry ELISA Flow Cytometry Immunocytochemistry
应用说明	Immunohistochemistry: for use on acetone or paraformaldehyde fixed tissue Immunocytochemistry: for use on B cells, PBL, T cells Immunoprecipitation FACS ELISA Inhibits ICAM-1 dependent adhesive interactions Optimal working dilutions must be determined by end user.

生物信息
免疫原品种	IL-1beta activated HUVEC (human)
克隆	P2A4
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	Human ICAM-1
同种型	IgG1
品种反应性	Human
抗体类型	Monoclonal Antibody
Entrez基因编号	NM_000201.1
Entrez基因汇总	ICAM1 (CD54) is typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. ICAM1 is also exploited by Rhinovirus as a receptor.
基因符号	ICAM-1 ICAM1 P3.58 BB2 CD54
UniProt编号	P05362
UniProt汇总	FUNCTION: SwissProt: P05362 # ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). In case of rhinovirus infection acts as a cellular receptor for the virus. Also acts as receptor for some coxsackieviruses. SIZE: 532 amino acids; 57825 Da SUBUNIT: Interacts with human herpesvirus 8 MIR2 protein (Probable). SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. PTM: Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. SIMILARITY: SwissProt: P05362 ## Belongs to the immunoglobulin superfamily. ICAM family. & Contains 5 Ig-like C2-type (immunoglobulin-like) domains.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain at +2-8°C.

包装信息
数量	100 µg

merck millipore,默克密理博,MAB2146,Anti-ICAM-1 Antibody, clone P2A4

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