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merck millipore,默克密理博,MAB1668,Anti-Phospholipase A2 Antibody, clone CH-7
产品名称:Anti-Phospholipase A2 Antibody, clone CH-7
产品型号:MAB1668
Detect Phospholipase A2 using this Anti-Phospholipase A2 Antibody, clone CH-7 validated for use in ELISA & WB.
merck millipore,默克密理博,MAB1668,Anti-Phospholipase A2 Antibody, clone CH-7
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 rH WB, ELISA M Purified Monoclonal Antibody 描述 产品目录编号 MAB1668 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Phospholipase A2 Antibody, clone CH-7 Alternate Names - PLA2
产品信息 格式 Purified 演示 In 20 mM sodium phosphate, 250 mM sodium chloride, 0.1% sodium azide, pH. 7.6 应用 应用 Detect Phospholipase A2 using this Anti-Phospholipase A2 Antibody, clone CH-7 validated for use in ELISA & WB. 主要应用 - Western Blotting
- ELISA
应用说明 Immunoblot: 1:500-1:1000; antibody recognizes all isoforms, the cPLA.
Alpha (85kDa) typically migrates as 100-110kDa on reducing westerns; beta migrates as 114kDa; antibody will also recognize the sPLA at approximately 14-20kDa.
ELISA
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Recombinant cPLA2 expressed from the human cPLA2 gene. 克隆 CH-7 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 Antibody reacts with cytosolic form of PLA2. Antibody will also react with beta isoform. Epitope has been localized within the first 216 aa of the N-terminal Ca++ binding domain of cPLA2 同种型 IgG2b 品种反应性 Recombinant Human Protein 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_000928.2
Entrez基因汇总 Phospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2 enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine, macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al., 1986 [PubMed 3028739]) .[supplied by OMIM] 基因符号 - EC 3.1.1.4
- PLA2G1B
- MGC119834
- PPLA2
- PLA2
- PLA2A
- MGC119835
修改 - Phosphorylation
UniProt编号 - P04054
UniProt汇总 FUNCTION: SwissProt: P04054 # PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides.
COFACTOR: Binds 1 calcium ion per subunit (By similarity).
SIZE: 148 amino acids; 16360 Da
SUBCELLULAR LOCATION: Secreted.SIMILARITY:SwissProt: P04054 ## Belongs to the phospholipase A2 family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C. 包装信息 数量 100 µg
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