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merck millipore,默克密理博,05-1360,Anti-RBMS1(MSSP-1) Antibody, clone 4D11
产品名称：Anti-RBMS1(MSSP-1) Antibody, clone 4D11
产品型号：05-1360
Anti-RBMS1(MSSP-1) Antibody, clone 4D11 is a Mouse Monoclonal Antibody for detection of RBMS1(MSSP-1) & has been validated in WB, ICC.
merck millipore,默克密理博,05-1360,Anti-RBMS1(MSSP-1) Antibody, clone 4D11
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H ICC, WB M Purified Monoclonal Antibody 描述 产品目录编号 05-1360 描述 Anti-RBMS1(MSSP-1) Antibody, clone 4D11 Alternate Names - suppressor of cdc 2 (cdc13) with RNA binding motif 2
- RNA binding motif, single stranded interacting protein 1
- Single-stranded DNA-binding protein MSSP-1
- Suppressor of CDC2 with RNA-binding motif 2
- c-myc gene single strand binding protein 2
背景信息 RNA-binding motif, single-stranded-interacting protein 1 (RBMS1 or MSSP-1) is a single-stranded DNA binding protein that is characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. At the developmental stage, RBMS1 (MSSP-1) is expressed at its highest levels during the G1 to S transition of the cell cycle and is most commonly found in placenta, lung and heart tissue. RBMS1 (MSSP-1) has been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. 产品信息 格式 Purified 控制 - MCF-7 cell lysate
演示 Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-RBMS1(MSSP-1) Antibody, clone 4D11 is a Mouse Monoclonal Antibody for detection of RBMS1(MSSP-1) & has been validated in WB, ICC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunocytochemistry Analysis: A previous lot of this antibody was used in confocal fluorescent analysis of NIH/3T3 and A431 cells (See page 2). 生物信息 免疫原品种 GST-tagged recombinant protein corresonding to RBMS1 (MSSP-1). 克隆 4D11 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 This antibody detects RBMS1 (MSSP-1). 同种型 IgG2bκ 品种反应性 MouseHuman Species Reactivity Note Demonstrated to react with human and mouse. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_002888.1
Entrez基因汇总 This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. 基因符号 - YC1
- MGC15146
- MGC3331
- MSSP
- MSSP-1
- MSSP-2
- MSSP-3
- MSSP1
- SCR2
纯化方法 Protein G purfied UniProt编号 - P29558
UniProt汇总 FUNCTION: Single-stranded DNA binding protein that interacts with the region upstream of the C-myc gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication.
SUBCELLULAR LOCATION: Nucleus.
TISSUE SPECIFICITY: Highest amounts are found in placenta, lung and heart.
DEVELOPMENTAL STAGE: Expressed at highest levels during the G1 to S transition of the cell cycle.
SEQUENCE SIMILARITIES: Contains 2 RRM (RNA recognition motif) domains.
SEQUENCE CAUTION: The sequence AAX93095.1 differs from that shown. Reason: Erroneous gene model prediction.
The sequence CAA45923.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
The sequence CAA45923.1 differs from that shown. Reason: Frameshift at positions 319 and 360.
产品使用声明 质量保证 Evaluated by Western Blot in MCF-7 cell lysate.
Western Blot Analysis: 1-2 µg/mL of this antibody detected RBMS1 (MSSP-1) on 15 µg of MCF-7 cell lysate.
使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable at 2-8°C for 1 year from date of receipt. 包装信息 数量 100 µg
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